BACE Inhibitor definition

BACE Inhibitor means (i) a compound that at Vitae inhibits human BACE enzyme activity by **** in an in vitro assay in which the Vitae inhibitor standard, ****, has an **** in an assay following the protocol as currently performed at Vitae and/or (ii) a compound that at BI inhibits human BACE enzyme activity by **** in in vitro assays in which the BI standard inhibitor, **** in assays following the protocols as currently performed at BI.
Sample 1Sample 2Sample 3

Examples of BACE Inhibitor in a sentence

  • During the Research Term (including any extensions of the initial Research Term), the BI Group, Vitae and Vitae’s Affiliates (except an Acquiring Entity) shall not, directly or with any Third Party, conduct Research, Development or Commercialization activities involving any BACE Inhibitor in the Field outside of this Research Collaboration, except as permitted pursuant to Sections 2.2, 2.5 and 3.3.2(k) (Vitae’s right to Research, Develop and Commercialize Non-Core BACE Inhibitors).

  • Vitae has furnished BI with all material information that is in Vitae’s possession and was requested by BI concerning Vitae’s BACE Inhibitor program, and, to Vitae’s knowledge, such information is accurate and complete in all material respects.

  • BI has decided to advance either BACE Inhibitor ****or BACE Inhibitor **** to Development Candidate Selection and agrees to pay the milestone payment according to Section 9.3.1 of the Agreement.

  • Notwithstanding the foregoing, Vitae shall provide the JSC at least twice yearly with a summary of the Development and CONFIDENTIAL TREATMENT REQUESTEDBACE RESEARCH COLLABORATION AND LICENSE AGREEMENTCommercialization activities pertaining to any Non-Core BACE Inhibitor.

  • BI BACE Compound” means a compound that (i) is a BACE Inhibitor, and (ii) (a) was discovered by the BI Group on or before the Effective Date, or (b) is in-licensed by the BI Group during the Research Term.

  • CONFIDENTIAL TREATMENT HAS BEEN REQUESTED WITH RESPECT TO THE OMITTED PORTIONS.Page 15 of 64 Commercialization activities pertaining to any Non-Core BACE Inhibitor.

Related to BACE Inhibitor

  • Biomarker means a parameter or characteristic in a patient or Patient Sample, the measurement of which is useful (a) for purposes of selecting appropriate therapies or patient populations or monitoring disease susceptibility, severity or state, or monitoring therapies for such patient and/or (b) for predicting the outcome of a particular treatment of such patient.

  • Receptor means enclosed spaces, conduits, protected groundwater sources, drinking and non-drinking water wells, surface water bodies, and public water systems which when impacted by chemicals of concern may result in exposure to humans and aquatic life, explosive conditions or other adverse effects on health, safety and the environment as specified in these rules.

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Diagnostic Product means any test or assay for diagnosing or detecting a disease, disorder, medical condition, or symptom.

  • Collaboration Compound means any of the following: (a) FG-4592, (b) any HIF Compound (other than FG-4592) that is added to this Agreement pursuant to Section 3.6, and (c) any salts, esters, complexes, chelates, crystalline and amorphous morphic forms, pegylated forms, enantiomers (excluding regioisomers), prodrugs, solvates, metabolites and catabolites of any of the foregoing ((a) or (b)).

  • Gene Therapy means a product or service for the treatment or prevention of a disease that utilizes ex vivo or in vivo delivery (via viral or nonviral gene transfer methods or systems) of Genetic Material, including any cell incorporating Genetic Material.

  • Collaboration Product means any pharmaceutical product in finished form that contains a Collaboration Compound, either as the sole active ingredient or in combination with one or more other active ingredients, and all present and future formulations, dosages and dosage forms thereof.

  • Licensed Compound means [***].

  • Biological agent shall mean any pathogenic (disease producing) micro-organism(s) and/or biologically produced toxin(s) (including genetically modified organisms and chemically synthesized toxins) which cause illness and/or death in humans, animals or plants.

  • Biological product means a virus, therapeutic serum, toxin, antitoxin, vaccine, blood, blood component or derivative, allergenic product, protein other than a chemically synthesized polypeptide, or analogous product, or arsphenamine or any derivative of arsphenamine or any other trivalent organic arsenic compound, applicable to the prevention, treatment, or cure of a disease or condition of human beings.

  • Cannabinoid means any of the chemical compounds that are the active constituents of marijuana.

  • Licensed Compounds means any EZH2 Compound(s) that is:

  • HIV means human immunodeficiency virus.