Examples of DTG in a sentence
DTG curves (A) and contents of brushite and remaining calcium carbonate (B) of the filtered solid products at different reaction times.
The main purpose of this visit is to collect an additional sparse PK sample to enrich population PK modeling for these participants, given the potential for prior NNRTI exposure to affect observed concentrations of DTG.
This is a Phase I/II study whose primary objectives are to assess the safety and pharmacokinetics of DTG administered to HIV-1-infected infants, children and adolescents with ages ranging from 4 weeks to < 18 years.
DTG was well tolerated with only mild adverse events described including diarrhea, fatigue, and headache.
Refer to the selected Dosing Table.• Participants who add EFV, FPV/r, or TPV/r as part of OBT after intensive PK will have the frequency of the dose of DTG changed to twice daily.• The initial dose of dispersible tablets will be administered in the clinic and observed by study staff for tolerability.
The pharmacokinetic evaluation should be scheduled so that the pre-dose PK samples and the witnessed dosing of DTG are as close as possible to 24 hours (generally 22-26 hours) after the previous dosing.
Results from Study ING112961 concluded DTG 50 mg BID with an optimized background provided greater and more durable benefit than the once-daily regimen in patients with prior RAL treatment failure.
DTG will be generally well tolerated and demonstrate an acceptable safety profile, adequate PK and antiviral activity when used concurrently with an optimized background therapy (OBT) in HIV-1 infected infants, children and adolescents.
EXAMPLE−GG KDZZNAXX DTG KCOUYFYX)SVC RQ FDC LOC=MCINOTE−All facilities must use their particular equipment’s keyboard equivalent of the closed parenthesis or equal symbol as appropriate.
Information to include on the form: Month, Facility, NOTAM Number, Condition Description, Transmitted by/ DTG, and Canceled by/DTG.b. Incoming FDC NOTAMs and cancellations must be logged on a locally approved form, containing at least the same data.