Radiopharmaceuticals. Radiopharmaceuticals prescribed by basically Act on Ensuring Quality, Effectiveness and Safety of Pharmaceuticals and Medical Devices,etc. (Act No. 145 of August 10, 1960) Their radionuclides were prescribed by the Atomic Energy Basic Act (Act No.186 of December 19, 1955) and they were also approved under Act on Ensuring Quality, Effectiveness and Safety of Pharmaceuticals and Medical Devices,etc. Radiopharmaceuticals are used mainly for injections, namely “in vivo use”. The assay kits containing Ⅳ radiolabeled compounds are also described as radiopharmaceuticals, namely “in vitro use” as long as they are used for clinical examinations. Radiopharmaceuticals are, here, described as “in vivo” for clinical diagnosis Ⅳ and therapy , and “in vitro” for diagnostic assays.
