Cautions Cardiovascular Sample Clauses

Cautions Cardiovascular. Cardiomyopathy has been reported with chronic amfetamine use.Sudden death has been reported in association with the use of stimulants of the central nervous system.Although some structural cardiac abnormalities alone maycarry an increased risk of sudden death, stimulant products are not recommended in adults with known structural cardiac abnormalities. Cardiovascular status should be carefully monitored. Blood pressure and pulse should be measured at each adjustment of dose and then at least every 3 months. Psychiatric disorders Co-morbidity of psychiatric disorders in ADHD is common and should be taken into account when prescribing stimulant products. In the case of emergent psychiatric symptoms or exacerbation of pre-existing psychiatric disorders, dexamfetamine should not be given unless the benefits outweigh the risks to the patient. Suicidal tendency Patients with emergent suicidal ideation or behaviour during treatment for ADHD should be evaluated immediately by their physician. Consideration should be given to the exacerbation of an underlying psychiatric condition and to a possible causal role of methylphenidate treatment. Treatment of an underlying psychiatric condition may be necessary and consideration should be given to a possible discontinuation of methylphenidate. Tics Dexamfetamine is associated with the onset or exacerbation of motor and verbal tics. Worsening of Tourette's syndrome has also been reported. Family history should be assessed and clinical evaluation for tics or Tourette's syndrome should precede use of methylphenidate. Patients should be regularly monitored for the emergence or worsening of tics during treatment with dexamfetamine. Monitoring should be at every adjustment of dose and then at least every 6 months or every visit. Seizures Dexamfetamine should be used with caution in patients with epilepsy. Dexamfetamine may lower the convulsive threshold in patients with prior history of seizures, in patients with prior EEG abnormalities in absence of seizures, and rarely in patients without a history of convulsions and no EEG abnormalities. If seizure frequency increases or new- onset seizures occur, dexamfetamineshould be discontinued Withdrawal Careful supervision is required during withdrawal, since this may unmask depression as well as chronic over-activity. Some patients may require long-term follow-up. Abuse, misuse and diversion Patients should be carefully monitored for the risk of diversion, misuse and abuse of dexamfe...
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