Construction and use of organoids Sample Clauses

Construction and use of organoids. Specific aspects of the consent considering the future use of the organoids are addressed in this the following sections. Organoids are simplified models of organs, composed of specific cell types which, when placed in suitable culture and environmental conditions, self-organise in three dimensions. The origin of the cells needed to construct an organoid is diverse, depending on whether they are derived from, or are pluripotent or adult stem cells from various organs. Embryonic pluripotent stem cells (ESCs) or induced pluripotent stem cells (iPSCs) have the particularity of being able to give rise to more than 200 cell types representative of all the tissues of the body. Multipotent stem cells, as are adult stem cells are derived from foetal or adult tissues with the particularity of giving rise to one or more cell types. In grafts, they ensure tissue renewal. Tumoroids are formed from tumour stem cells contained in biopsies or surgical removal of tumours.
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Construction and use of organoids 

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