Generation and Analysis of Mutant Mice Sample Clauses

Generation and Analysis of Mutant Mice. In the Target Discovery Program, Lexicon shall complete (a) the development and Xxxxx 0 Xxxxxxxxxx Xxxxxxxx of Four Thousand (4,000) lines of Mutant Mice and (b) Level 2 Phenotypic Analysis of such lines of Mutant Mice, from the first Three Thousand (3,000) lines of Mutant Mice for which Level 1 Phenotypic Analysis was completed, that displayed a phenotype suggestive, as determined by the Joint Scientific Committee, of the potential utility of the corresponding Target in the CNS Field. All lines of Mutant Mice developed by Lexicon prior to the Effective Date (including but not limited to those for which Xxxxx 0 Xxxxxxxxxx Xxxxxxxx xxx/xx Xxxxx 0 Xxxxxxxxxx Analysis was completed prior to the Effective Date), with the exception of LG617, shall be included in the Target Discovery Program. Lexicon shall use Diligent Efforts to complete such work by the end of the third Contract Year of the Research Term and, if necessary, shall continue to use Diligent Efforts thereafter until such work is complete, without further annual research funding by BMS (subject to Section 2.2.2). The Target Discovery Program Term shall continue until such work is complete.
Sample 1
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Generation and Analysis of Mutant Mice. The parties acknowledge and agree that, as of the Effective Date, Lexicon has completed the development and Xxxxx 0 Xxxxxxxxxx Xxxxxxxx of Mutant Mice for each Program Target that has not become a Released Target or Reverted Target. During the balance of the Target Function Discovery Program, Lexicon shall use Diligent Efforts to complete Xxxxx 0 Xxxxxxxxxx Xxxxxxxx of lines of Mutant Mice under the supervision of the Joint Research Committee and to the extent and degree specified in the Predecessor Agreement.
Sample 1
Generation and Analysis of Mutant Mice. In the Target Discovery Program, Lexicon shall complete (a) the development and Xxxxx 0 Xxxxxxxxxx Xxxxxxxx of [**] lines of Mutant Mice and (b) Level 2 Phenotypic Analysis of such lines of Mutant Mice, from the first [**] lines of Mutant Mice for which Level 1 Phenotypic Analysis was completed, that displayed a phenotype suggestive, as determined by [**], of the potential utility of the corresponding Target in the CNS Field. All lines of Mutant Mice developed by Lexicon [**] shall be [**]. Lexicon shall use Diligent Efforts to complete such work by the end of the third Contract Year of the Research Term and, if necessary, shall continue to use Diligent Efforts thereafter until such work is complete, [**]. The Target Discovery Program Term shall continue until such work is complete.
Sample 1
Generation and Analysis of Mutant Mice. In the Target Function Discovery Program, Lexicon shall use Diligent Efforts to complete (a) the development and Level 1 Phenotypic Analysis of Mutant Mice for each Program Xxxxxx xxx (x) Xxxxx 0 Xxxxotypic Analysis of such lines of Mutant Mice that displayed a phenotype suggestive, as determined by the Joint Research Committee, of the potential utility of the corresponding Program Target in the Collaboration Field.
Sample 1
Generation and Analysis of Mutant Mice. In the Target Discovery Program, Lexicon shall complete (a) the development and Lxxxx 0 Xxxxxxxxxx Xxxxxxxx of [**] lines of Mutant Mice and (b) Level 2 Phenotypic Analysis of such lines of Mutant Mice, from the first [**] lines of Mutant Mice for which Level 1 Phenotypic Analysis was completed, (1) that displayed a phenotype suggestive, as determined by [**], of the potential utility of the corresponding Target in the CNS Field or (2) with respect to which any other information is identified, including but not limited to expression levels in brain tissues, that is suggestive, as determined by [**], of the potential utility of the corresponding Target in the CNS Field. All lines of Mutant Mice developed by Lexicon [**] shall be [**]. Lexicon shall use Diligent Efforts to complete such work by the end of the third Contract Year of the Research Term and, if necessary, shall continue to use Diligent Efforts thereafter until such work is complete [**]. The Target Discovery Program Term shall continue until such work is complete.
Sample 1
Generation and Analysis of Mutant Mice. In the Target Discovery Program, Lexicon shall complete (a) the development and Level 1 Phenotypic Analysis of [**] lines of Mutant Mice and (b) Levxx 0 Xxxxxxxxxx Xxxxxxxx xx such lines of Mutant Mice, from the first [**] lines of Mutant Mice for which Level 1 Phenotypic Analysis was completed, that displayed a phenotype suggestive, as determined by [**], of the potential utility of the corresponding Target in the CNS Field. [**]. Lexicon shall use Diligent Efforts to complete such work by the end of the third Contract Year of the Research Term and, if necessary, shall continue to use Diligent Efforts thereafter until such work is complete, [**]. The Target Discovery Program Term shall continue until such work is complete.
Sample 1

Related to Generation and Analysis of Mutant Mice

  • Sampling and Analysis The sampling and analysis of the coal delivered hereunder shall be performed by Buyer upon delivery of the coal to Buyer’s facility, and the results thereof shall be accepted and used as defining the quality and characteristics of the coal delivered under this Agreement and as the Payment Analysis. All analyses shall be made in Buyer’s laboratory at Buyer’s expense in accordance with ASTM standards where applicable, or industry-accepted standards in other cases. Samples for analyses shall be taken in accordance with ASTM standards or other methods mutually acceptable to both parties. Seller shall transmit its “as loaded” quality analysis to Buyer as soon as possible. Seller’s “as-loaded” quality shall be the Payment Analysis only when Buyer’s sampler and/or scales are inoperable, or if Buyer fails to obtain a sample upon unloading. Seller represents that it is familiar with Buyer’s sampling and analysis practices, and that it finds them to be acceptable. Buyer shall notify Seller in writing of any significant changes in Buyer’s sampling and analysis practices. Any such changes in Buyer’s sampling and analysis practices shall, except for ASTM or industry-accepted changes in practices, provide for no less accuracy than the sampling and analysis practices existing at the tune of the execution of this Agreement, unless the Parties otherwise mutually agree. Each sample taken by Buyer shall be divided into four (4) parts and put into airtight containers, properly labeled and sealed. One (1) part shall be used for analysis by Buyer. One (1) part shall be used by Buyer as a check sample, if Buyer in its sole judgment determines it is necessary. One (1) part shall be retained by Buyer until thirty (30) days after the sample is taken (“Disposal Date”), and shall be delivered to Seller for analysis if Seller so requests before the Disposal Date. One (1) part (the “Referee Sample”) shall be retained by Buyer until the Disposal Date. Seller shall be given copies of all analyses made by Buyer by the fifth (5th) business day of the month following the month of unloading. In addition, Buyer shall send Seller weekly analyses of coal unloaded at Buyer’s facilities. XXXXXXXXX COAL COMPANY, INC. LG&E/KU Xxxxxxxx Xx. X00000 Seller, on reasonable notice to Buyer, shall have the right to have a representative present to observe the sampling and analyses performed by Buyer. Unless Seller requests an analysis of the Referee Sample before the Disposal Date, Buyer’s analysis shall be used to determine the quality of the coal delivered hereunder and shall be the Payment Analysis. The Monthly Weighted Averages of specifications referenced in §6.1 shall be based on the individual Shipment analyses. If any dispute arises with regard to the analysis of any sample before the Disposal Date for such sample, the Referee Sample retained by Buyer shall be submitted for analysis to an independent commercial testing laboratory (“Independent Lab”) mutually chosen by Buyer and Seller. For each coal quality specification in question, if the analysis of the Independent Lab differs by more than the applicable ASTM reproducibility standards, the Independent Lab results will govern, and the prior analysis shall be disregarded. All testing of the Referee Sample by the Independent Lab shall be at requestor’s expense unless the Independent Lab results differ from the original Payment Analysis for any specification by more than the applicable ASTM reproducibility standards as to that specification. In such case, the cost of the analysis made by the Independent Lab shall be borne by the party who provided the original Payment Analysis. XXXXXXXXX COAL COMPANY, INC. LG&E/KU Contract No. J12004

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  • Quantitative Analysis Quantitative analysts develop and apply financial models designed to enable equity portfolio managers and fundamental analysts to screen potential and current investments, assess relative risk and enhance performance relative to benchmarks and peers. To the extent that such services are to be provided with respect to any Account which is a registered investment company, Categories 3, 4 and 5 above shall be treated as “investment advisory services” for purposes of Section 5(b) of the Agreement.”

  • Investment Analysis and Implementation In carrying out its obligations under Section 1 hereof, the Advisor shall:

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