Key Findings and Conclusions. Please explain your key findings including any reason for any variance from your original proposals both overall and within the Programme itself.
Key Findings and Conclusions. This study examined the impact of COC at baseline on experiencing functional decline in the subsequent year among the older adults with ADRD using a logistic regression, and further examined the marginal effects among a limited study sample of older patients without functional difficulties at baseline. Although I didn’t find a statistically significant effect of COC at baseline on experiencing functional decline in the subsequent year among the complete study sample, this agrees with current literature. Higher level of COC, however, was found to be associated with 7.51% lower incidence of functional decline (measured in ADL) in the subsequent year among those without functional difficulties. Additionally, when evaluating functionality using IADL categories, the involvement of PCP is associated with 25.8% lower chance of experiencing functional decline in the subsequent year. COC for older adults with ADRD was found to be statistically significant beneficial in preventing and/or delaying short-term functional decline (within one-year time lag) among those without difficulties in functionality at baseline. Beyond survival, patients value most their functional health, the preservation of functionality is shown to be highly correlated with their quality of life.[26,66] Additionally, for the patients’ families and/or caregivers, they would face less burden of assisting the patients with ADL on top of their memory loss and cognitive deterioration. On a societal level, studies have shown that functional capacity has a significant effect on the patients’ quality of life, and Xxxxxxxxx et al. (2017) have estimated that if the rate of functional decline among older adults with ADRD reduces by 10 percent, it would reduce average per-person lifetime costs by $4,122 in 2018 dollars.[9]
