Methods of addressing contamination Sample Clauses

Methods of addressing contamination. ‌ I distinguish between three types of methods that are used to address contamination. These categories are named here as statistical design, trial conduct and analytical met- hods. The first refers to structural aspects of trial design such as the level at which treatment is allocated, sample size inflation, and participant preference designs. The second includes trial implementation methods that are used to minimise the process by which participants’ treatment becomes contaminated. The third relies on there being a measurement of individual treatment receipt and includes comparison of groups based on treatment received using randomisation-based estimation methods from the causal inference literature.
Sample 1
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