Rotavirus Vaccine Efficacy in Developing Nations Sample Clauses

Rotavirus Vaccine Efficacy in Developing Nations. 1.4.1 Rates of vaccine efficacy in developing nations In developing countries, the efficacy of RV vaccines is less than in developed countries. For example, Rotarix only provides 50% protection in Malawi, 77% protection in South Africa, and 85% protection in Latin America against RV diarrhea. This is in contrast with protection rates in developed nations where protection reaches upwards of 96% (12). In addition to protection rates, vaccine seroconversion rates are also blunted in developing nations; serum IgA seroconversion after Rotarix administration is markedly reduced in low-income countries than in high-income countries (13). This difference in vaccine efficacy between nations is not attributed to a discordance between circulating RV strains and RV strains included in the vaccines and instead suggests that differences between individuals may contribute to vaccine in efficacy (14).
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Related to Rotavirus Vaccine Efficacy in Developing Nations

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