Lead-time bias definition

Lead-time bias means that screening speeds up detection, so incidence is higher in the study group at the beginning of followup. ‘Length bias’ means that screening is likely to pick up slower- rather than faster-growing tumors. However, clinical trials like HIP or Two-County are skewed by neither bias, because (i) they use death from breast cancer as the endpoint not detection rates or lifespan after detection, and (ii) they use intention-to-treat analyses. Indeed, that is why attention is restricted to evidence from clinical trials.46
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Related to Lead-time bias

  • Lead Time means the quoted timeframe calculated between the date of receipt of the PO by Supplier and the Delivery Date.

  • Purchase Order (PO) means a written offer made by a purchaser to a supplier formally stating the terms and conditions of a proposed transaction.

  • RFQ means Request for Quotation.

  • Proposal Due Date and Time means the date and time specified in the Request for Proposal as the deadline for submitting Proposals.

  • Drug sample means a unit of a prescription drug that is not intended to be sold and is intended to promote the sale of the drug.

  • BOM means Board of Management.

  • Prime coat means the first of two or more films of coating applied to a metal surface.

  • Minimum Order Quantity means the minimum number of batches of a Product to be produced during the same cycle of manufacturing as set forth in a Product Agreement on Schedule B;

  • product type means any of the following:

  • Delivery Schedule means the schedule for the delivery of Services as set forth in attached Annex 3.

  • Job-order-contracting means a project delivery method in which:

  • Contract Schedule means a schedule to this Contract;

  • Design-build team means an entity that consists of:

  • Purchase Order means the form or format a Customer uses to make a purchase under the Contract (e.g., a formal written purchase order, electronic purchase order, procurement card, contract or other authorized means).

  • Purchase Orders means official orders issued by an operating division of Transnet to the Supplier/Service Provider for the supply of Goods or Services;

  • Expiry Date (Data di Scadenza) means the "Expiry Date" as specified in § 1 of the Product and Underlying Data.

  • SAP Training Catalogue means the catalogue published by SAP containing details of SAP training courses and services.

  • Contract Specifications means the principal trading terms in CFD (for example Spread, Swaps, Lot Size, Initial Margin, Necessary Margin, Hedged Margin, the minimum level for placing Stop Loss, Take Profit and Limit Orders, financing charges, charges etc) for each type of CFD as determined by the Company from time to time.

  • SOQ means Statement of Qualifications.

  • Non-Microsoft Product means any third-party-branded software, data, service, website or product, unless incorporated by Microsoft in a Product.

  • Product Schedule means PTC’s standard order form entitled “PTC Product Schedule” (including all schedules, attachments and other document(s) specifically referenced therein) or such alternative order form as may be submitted by Customer and accepted by PTC, in each case that specifies (i) the Licensed Products and/or Services ordered; and (ii) for Licensed Products, the installation address (including the Designated Country) and the Licence Term.

  • Contract Quantity means the quantity of Gas to be delivered and taken as agreed to by the parties in a transaction.

  • KPI means a key performance indicator to which the Services are to be provided as set out in the Specification].

  • Contract Sum means the sum named in the letter of acceptance including Physical contingencies subject to such addition thereto or deduction there-from as may be made under the provisions hereinafter contained.

  • BOQ means Bill of Quantity or the Price Schedule in which rates for the e-tender should be quoted and uploaded online on the e-tender website.

  • IITK Purchase Order means the IITK’s official Purchase Order document;