Linearized multistage model definition

Linearized multistage model means a conservative mathematical model for cancer risk assessment. This model fits linear dose-response curves to low doses. It is consistent with a no-threshold model of carcinogenesis, that is, exposure to even a very small amount of the substance is assumed to produce a finite increased risk of cancer.
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Linearized multistage model means a conservative mathematical model for cancer risk assessment. The model fits linear dose-response curves to low doses. The model is consistent with a no-threshold model of carcinogenesis.
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Linearized multistage model means a dose-response model which assumes that there are a number of distinct biological stages or changes that must occur for a normal cell to be transformed into a tumor and which assumes the dose-response relationship to be linear at low doses.
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More Definitions of Linearized multistage model

Linearized multistage model means a conservative mathematical model for cancer risk assessment. This model fits linear dose-response curves to low doses. It is consistent with a no-threshold model of carcinogenesis, i.e., exposure to even a very small amount
Sample 1Sample 2
Linearized multistage model means a dose-response model which assumes that there are a number of distinct biological stages or changes that must occur for a normal cell to be transformed into a tumor and which assumes the dose-response relationship to be linear at low doses.modification of the multistage dose-response model, used for estimating carcinogenic risk, that incorporates a linear upper bound on extra risk for exposures below the experimental range.
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