Linearized multistage model means a conservative mathematical model for cancer risk assessment. This model fits linear dose-response curves to low doses. It is consistent with a no-threshold model of carcinogenesis, that is, exposure to even a very small amount of the substance is assumed to produce a finite increased risk of cancer.
Linearized multistage model means a conservative mathematical model for cancer risk assessment. The model fits linear dose-response curves to low doses. The model is consistent with a no-threshold model of carcinogenesis.
Linearized multistage model means a dose-response model which assumes that there are a number of distinct biological stages or changes that must occur for a normal cell to be transformed into a tumor and which assumes the dose-response relationship to be linear at low doses.
Examples of Linearized multistage model in a sentence
Linearized multistage model" means a conservative mathematical model for cancer risk assessment.
More Definitions of Linearized multistage model
Linearized multistage model means a conservative mathematical model for cancer risk assessment. This model fits linear dose-response curves to low doses. It is consistent with a no-threshold model of carcinogenesis, i.e., exposure to even a very small amount
Linearized multistage model means a dose-response model which assumes that there are a number of distinct biological stages or changes that must occur for a normal cell to be transformed into a tumor and which assumes the dose-response relationship to be linear at low doses.modification of the multistage dose-response model, used for estimating carcinogenic risk, that incorporates a linear upper bound on extra risk for exposures below the experimental range.