Major Cancer definition

Major Cancer means a malignant tumour characterised by the uncontrolled growth and spread of malignant cells with invasion and destruction of normal tissue. This Diagnosis must be supported by histological evidence of malignancy and confirmed by an oncologist or pathologist.
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Major Cancer means the occurrence of (i) or (ii): (i) Any malignant tumour positively Unequivocally Diagnosed with histological confirmation and characterized by the uncontrolled growth of malignant cells and invasion of tissue; or(ii) Any occurrence of histologically confirmed leukemia, lymphoma or sarcoma. Irrespective of the above, Major Cancer does not include carcinoma-in-situ.“Public Health Emergency of International Concern”shall mean a formal declaration by the World Health Organization of an extraordinary event which is determined to constitute a public health risk to other states through the international spread of disease and to potentially require a coordinated international response, which is still valid and not expired on the date of Unequivocal Diagnosis.“Respiratory Diseases”shall mean an Unequivocal Diagnosis of any one (1) of the following conditions:(i) End Stage Lung Disease(ii) Single or Double-Lung Transplant(iii) Severe Asthma(iv) Severe Bronchiectasis(v) Severe Chronic Obstructive Lung Disease(vi) Severe Emphysema(vii) Severe Pulmonary Fibrosis(viii) Single-Lung Surgery The Unequivocal Diagnosis must be confirmed by a Specialist in the relevant medical field.“Severe Asthma”shall mean the Insured Person suffering from severe asthma which is characterized by at least three (3) of the following:(i) history of status asthmaticus within the past two (2) years;(ii) significant and continuous reduction in exercise tolerance, as certified by a Registered Medical Practitioner;(iii) chest deformities resulting from chronic hyperinflation;(iv) the need for regular oxygen therapy at home as prescribed by a Registered Medical Practitioner; and(v) continuous daily use of oral corticosteroids (for a minimum period of six (6) consecutive months) as prescribed by a Registered Medical Practitioner.“Severe Bronchiectasis”shall mean an Unequivocal Diagnosis of severe bronchiectasis requiring Extensive and Permanent Oxygen Therapy as well as FEV 1 test result of consistently less than one (1) litre as certified by a Specialist in the relevant medical field. “Severe Chronic Obstructive Lung Disease” shall mean an Unequivocal Diagnosis of severe chronic obstructive lung disease requiring Extensive and Permanent Oxygen Therapy as well as FEV 1 test result of consistently less than one (1) litre as certified by a Specialist in the relevant medical field. “Severe Emphysema” shall mean an Unequivocal Diagnosis of severe emphysema requiring Extensive and Permanent Oxygen T...
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Major Cancer means the occurrence of (i) or (ii):
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Examples of Major Cancer in a sentence

  • The following Sections 1-15 including optional cover – “Extension of Section 3 and 5 due to Major Cancer and Heart Disease”, will apply based on the type of worker and the plan You have selected as shown in Your Policy Schedule.


More Definitions of Major Cancer

Major Cancer means a malignant tumour positively diagnosed with histological confirmation and characterised by the uncontrolled growth of malignant cells with invasion and destruction of normal tissue.The term Major Cancer includes, but is not limited to, leukemia, lymphoma and sarcoma.Major Cancer diagnosed on the basis of finding tumour cells and/or tumour-associated molecules in blood, saliva, faeces, urine or any other bodily fluid in the absence of further definitive and clinically verifiable evidence does not meet the above definition.The following shall not fall within the definition of “Major Cancer” and are not covered under this Policy:
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Major Cancer means a malignant tumour positively diagnosed with histological confirmation and characterised by the uncontrolled growth of malignant cells with invasion and destruction of normal tissue. The term Major Cancer includes, but is not limited to, leukemia, lymphoma and sarcoma. Major Cancer diagnosed on the basis of finding tumour cells and/or tumour-associated molecules in blood, saliva, faeces, urine or any other bodily fluid in the absence of further definitive and clinically verifiable evidence does not meet the above definition. For the above definition, the following are excluded: • All tumours which are histologically classified as any of the following:
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Related to Major Cancer

  • Stage-Four Advanced, Metastatic Cancer means a cancer that has spread from the primary or original site of the cancer to nearby tissues, lymph nodes, or other areas or parts of the body.

  • Clinical Trial means a Phase I Clinical Trial, Phase II Clinical Trial or Phase III Clinical Trial, or any post-approval human clinical trial, as applicable.

  • Phase II Clinical Trial means a controlled human clinical study that would satisfy the requirements of 21 CFR 312.21(b), conducted to study the effectiveness and establish the dose range of a Product for a particular Indication in patients with the disease or condition under study, including a Phase IIA Clinical Study or Phase IIB Clinical Study.

  • Phase 2 Clinical Trial means a human clinical trial, for which the primary endpoints include a determination of dose ranges or an indication of efficacy in patients being studied as described in 21 C.F.R. §312.21(b), or an equivalent clinical trial in a country in the Territory other than the United States.

  • Phase 3 Clinical Trial means a pivotal clinical trial in humans performed to gain evidence with statistical significance of the efficacy of a product in a target population, and to obtain expanded evidence of safety for such product that is needed to evaluate the overall benefit-risk relationship of such product, to form the basis for approval of an NDA and to provide an adequate basis for physician labeling, as described in 21 C.F.R. § 312.21(c) or the corresponding regulation in jurisdictions other than the United States.

  • Phase 3 Trial means a human clinical trial of a Product on a sufficient number of subjects that is designed to establish that a pharmaceutical product is safe and efficacious for its intended use, and to determine warnings, precautions and adverse reactions that are associated with such pharmaceutical product in the dosage range to be prescribed, which trial is intended to support Approval of a Product, as described in 21 C.F.R. 312.21(c) for the United States, or a similar clinical study prescribed by the Regulatory Authorities in a foreign country.

  • Phase III Clinical Trial means a large, controlled or uncontrolled Clinical Study that would satisfy the requirements of 21 CFR 312.21(c), intended to gather the additional information about effectiveness and safety that is needed to evaluate the overall benefit-risk relationship of the drug and to provide an adequate basis for physician labeling.

  • Phase 1 Clinical Trial means a Clinical Trial of a Product on sufficient numbers of normal volunteers and/or patients that is designed to establish that such Product is safe for its intended use and to support its continued testing in Phase 2 Clinical Trials. For purposes of this Agreement, ‘initiation’ of a Phase 1 Clinical Trial for a Product means the first dosing of such Product in a human subject in a Phase 1 Clinical Trial.

  • Phase 3 Study means a clinical study of an investigational product in patients that incorporates accepted endpoints for confirmation of statistical significance of efficacy and safety with the aim to obtain Marketing Approval in any country as described in 21 C.F.R. 312.21(c), or a comparable Clinical Study prescribed by the relevant Regulatory Authority in a country other than the United States. The investigational product can be administered to patients as a single agent or in combination with other investigational or marketed agents and a Phase 3 Study shall be deemed commenced when Initiated.

  • Phase I Clinical Trial means a study in humans which provides for the first introduction into humans of a product, conducted in normal volunteers or patients to generate information on product safety, tolerability, pharmacological activity or pharmacokinetics, or otherwise consistent with the requirements of U.S. 21 C.F.R. §312.21(a) or its foreign equivalents.

  • Study means the investigation to be conducted in accordance with the Protocol.

  • Pivotal Trial means a clinical study in humans of the efficacy and safety of a Licensed Product that is prospectively designed to demonstrate with statistical significance that such product is effective and safe for use in a particular indication in a manner sufficient to file for Marketing Approval of such product and would satisfy the requirements of 21 CFR 312.21(c), or a similar clinical study prescribed by the Regulatory Authorities in a country other than the United States.

  • Treatability study means a study in which a hazardous waste is subjected to a treatment process to determine: (1) Whether the waste is amenable to the treatment process, (2) what pretreatment (if any) is required, (3) the optimal process conditions needed to achieve the desired treatment, (4) the efficiency of a treatment process for a specific waste or wastes, or (5) the characteristics and volumes of residuals from a particular treatment process. Also included in this definition for the purpose of the § 261.4 (e) and (f) exemptions are liner compatibility, corrosion, and other material compatibility studies and toxicological and health effects studies. A “treatability study” is not a means to commercially treat or dispose of hazardous waste.