Analysis Methods. A mixed effect repeated measures model will be utilized to test these hypotheses. The model will include terms for lens, visit, lens by visit interaction, period, and sequence. Within- subject correlation due to eye and the crossover design will also be accounted for in the model. Lens difference (PRECISION1 minus Clariti 1-Day) and the corresponding one-sided 95% upper confidence limit will be computed. Noninferiority in distance VA will be declared if upper confidence limit is less than 0.05.
Appears in 1 contract
Samples: Investigator Agreement
Analysis Methods. A mixed effect effects repeated measures model will be utilized to test these hypotheses. The model will include terms for lens, visit, lens by visit interaction, period, and sequence. Within- subject correlation due to eye and the crossover design will also be accounted for in the model. Lens difference (PRECISION1 minus Clariti 1-Day) and the corresponding one-sided 95% upper confidence limit will be computedcomputed at Day 30. Noninferiority in distance VA will be declared if upper confidence limit is less than 0.05.
Appears in 1 contract
Samples: Investigator Agreement
Analysis Methods. A mixed effect repeated measures model will be utilized to test these hypotheses. The model will include terms for lens, visit, lens by visit interaction, period, and sequence. Within- Within-subject correlation due to eye and the crossover design will also be accounted for in the model. Lens difference (PRECISION1 DACP Digital minus Clariti 1-DayDACP) and the corresponding one-sided 95% upper confidence limit will be computedcomputed at 1-Week. Noninferiority in distance VA will be declared if upper confidence limit is less than 0.05.0.05.
Appears in 1 contract
Samples: classic.clinicaltrials.gov
Analysis Methods. A mixed effect repeated measures model will be utilized to test these hypotheses. The model will include terms for lens, visit, lens by visit interaction, period, and sequencesequence as fixed effects. Within- Within-subject correlation due to eye and the crossover design will also be accounted for in the model. Lens difference (PRECISION1 DT1 minus Clariti 1-DayInfuse) and the corresponding one-sided 95% upper confidence limit will be computed. Noninferiority in distance VA will be declared if upper confidence limit is less than 0.05.
Appears in 1 contract
Samples: Investigator Agreement
Analysis Methods. A mixed effect effects repeated measures model will be utilized to test these hypotheses. The model will include terms for lens, visit, lens by visit interaction, period, and sequence. Within- Within-subject correlation due to eye and the crossover design will also be accounted for in the model. Lens difference (PRECISION1 minus Clariti 1-DayBiotrue) and the corresponding one-sided 95% upper confidence limit will be computed. Noninferiority in distance VA will be declared if upper confidence limit is less than 0.05.
Appears in 1 contract
Samples: Investigator Agreement