Assessment of Dietary Intake Sample Clauses

Assessment of Dietary Intake. ‌ During the first month of BH4 therapy, patients were instructed to consume a diet consistent with their baseline intake, regardless of adherence to their diet prescription (the amount of dietary phenylalanine and medical food clinically advised to consume in a day). Patients were asked to submit 3-day diet records on a weekly basis, starting with their baseline study visit. If a 3-day diet record was not received, a metabolic dietitian attempted to capture a 24-hour recall. Diet records and recalls were analyzed using the Nutrition Data System for Research diet analysis program (2010 version, Nutrition Coordinating Center, University of Minnesota, Minneapolis, MN, USA). There were six dietary measures of interest captured from the diet records and recalls: energy, total protein, phenylalanine, phenylalanine prescription compliance, medical food protein equivalent, and medical food prescription compliance. Energy intake was evaluated to assess whether any identified trends were a function of change in overall consumption. Total protein represented the sum of intact protein and medical food protein equivalents, while phenylalanine served as a proxy for intact protein intake, as all medical foods were phenylalanine-free. Baseline dietary phenylalanine and medical food prescriptions were drawn from patients’ medical charts and compared to reported intake to evaluate diet prescription compliance. Compliance was expressed as a percent of the patient’s baseline diet prescription.