Dose Calculation for Dermal Contact Sample Clauses

Dose Calculation for Dermal Contact. The scenario used to evaluate potential hazards from dermal contact with groundwater assumes that a worker falls waist-deep (contact with one-half the total skin area) into a trench with groundwater contaminated at the maximum detected levels, once a week, throughout an anticipated three 287 TABLE 4-6 MAXIMUM DETECTED SHALLOW GROUNDWATER CONTAMINANT CONCENTRATIONS (VOLATILE ORGANICS, SEMI-VOLATILE ORGANICS, AND PESTICIDES) ----------------------------------------------------------------------------------- Compound Source Concentration (well) (ppm) ----------------------------------------------------------------------------------- *Acetone UGP-2 0.022 *Benzene P-1A 0.039 *Ethylbenzene WQ-4 2.9 *Toluene P-4 0.28 *1, 4-Dichlorobenzene P-1A 2.9 Bis (2-chloroisopropyl)ether S-4A 0.08 *Xylene P-1A 0.22 2-Methylphenol S-4A 0.07 4-Methylphenol S-4A 0.015 Isophorone S-4A 0.015 2, 4-Dimethylphenol P-1A 0.1 Naphthalene P-1A 0.11 4-chloro-3-methylphenol S-4A 0.03 2-Methylnaphthalene S-4A 0.09 Acenaphthene S-4A 0.02 Dibenzofuran S-4A 0.03 *Bis (2-ethylhexyl)phthalate P-24 0.31 *Perchloroethylene P-1A 0.097 Arocxxxx-0000 X-0 0.075 Gamma-BHC S-4A 0.00008 Delta-BHC K-4 0.0001 Beta-XXX X-0 0.00000 Xxxxxxxxxx X-0 0.0014 Aldrin K-4 0.00012 Heptachlor Epoxide K-4 0.0002 Endosulfan I K-4 0.00023 4, 4'-DDE K-4 0.00035 Dieldrin K-4 0.00019 Endrin K-4 0.00021 4,4'-DDD K-4 0.00026 Endosulfan II K-3 0.00023 4,4'-DDT K-4 0.00048 Endrin Aldehyde P-7 0.0004 Endosulfans sulfate S-4A 0.00008 ----------------------------------------------------------------------------------- Note: All values from McLaren (1989) groundwater sampling except those noted with an asterisk (*), which are Levixx Xxxcxx (0089a) values. 288 month construction period, and that the water remains in contact with the skin for one hour during each episode with a constant contaminant concentration. The scenario therefore assumes that no protective clothing is worn. The dermal absorption rate to be used in the analysis is one of the highest rates identified for all of the listed compounds. which is for perchloroethylene. The factors used in the calculation of dose per episode are as follows: (Chemical) = Benzene = 0.039 ppm Ethybenzene - 2.9 ppm area = 8768 cm(2) ET = 60 minutes DAR = 4 ug/cm(2)-min (Tsuruta, 1982) WT = 70 kg The calculated dose per episode for benzene is 1.2 x 10(-6) mg/kg and 8.7 x 10(-5) mg/kg ethylbenzene. Assuming twelve episodes (once a week for 3 months) the average daily lifetime (70 years) dose...
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