Landscape for gene panels Sample Clauses

Landscape for gene panels. We construct gene panels for 30 tissue types for which at least 10 samples were present in the current GTEx data. Figure 30 depicts distributions of gene panels with top 200 pre- selected candidate genes with default tuning parameters. Figure 30(a) indicates that most of the genes in the human genome have large enough panels to be used in following tasks. Although different tissues have a slightly shifted distributions, they share a common general pattern. We can further investigate the distribution of the number of
Sample 1
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Landscape for gene panels. (a) Distribution of number of genes included in the panel for different tissues. (b)-(d) Detailed distribution for liver, kidney and lung. The patterns for different tissues are slight different while they share some common trends. In general, low mean and low SD target genes can easily have a large panel while genes with high mean or high SD have much smaller ones. The patterns shown in Figure 30 (b) – (d) is as expected since high mean or high SD genes tend to be more variable and if could be extremely difficult to “impute” their values by similar genes.
Sample 1

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