Preparation of NADES Sample Clauses

Preparation of NADES. Two methods have been described for the preparation of DES: freeze-drying (Gutiérrez et al., 2009) and heating a mixture of the solids to around 80 oC (Abbott et al., 2003). The NADES evaluated in this study can be obtained by heating with stirring at 50 oC in 0.5-2h when adding a small amount of water. This method is not only cheaper but also safer considering that the components are usually thermally unstable, as is the case of sugars or amino acids. Both vacuum evaporating and heating methods tested in this paper show the same chemical profile for the liquid obtained as shown by the 1H NMR spectra.
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