Substituted Specimen one that has a creatinine of less than or equal to 5mg/dL and a specific gravity less than or equal to 1.001 or greater than or equal to 1.020. These specimens do not exhibit the clinical signs or characteristics associated with normal urine.
Substituted Specimen. A specimen with creatinine and specific gravity values that are so diminished that they are not consistent with human urine.
Substituted Specimen. “Substituted specimen” is a specimen with creatinine and specific gravity values that are so diminished that they are not consistent with human urine.
Substituted Specimen. The proposed rule would revise the definition of substituted specimen in § 26.5 to align with the definition of the term in Section 1.5 of the 2008 HHS Guidelines. The phrase ‘‘specimen with creatinine and specific gravity values that are so diminished or so divergent that they are not consistent with normal human physiology’’ would be replaced with ‘‘a specimen that has been submitted in place of the donor’s urine, as evidenced by creatinine and specific gravity values that are outside the physiologically producible ranges of human urine.’’ 4 The revision would also improve the clarity of the rule by explaining that a substituted specimen is the result of donor action to subvert the testing process by stating that the specimen ‘‘has been submitted in place of the donor’s urine.’’ Drug Testing Panel Additions The proposed rule would add two amphetamine-based chemical compounds: Methylenedioxymethamphetamine (MDMA) and methylenedioxyamphetamine (MDA) to the NRC-required drug testing panel, consistent with the drug testing panel in Section 3.4 of the 2008 HHS Guidelines. The 2008 HHS Guidelines also added an additional amphetamine-based chemical compound, methylenedioxyethylamphetamine (MDEA); however, in its 2017 mandatory guidelines (82 FR 7920;
Substituted Specimen a urine specimen that has been submitted in place of the CLIENT’s urine, as evidenced by creatinine and specific gravity values that are outside the physiologically producible ranges of human urine.
