Systemic Lupus Erythematous Sample Clauses

Systemic Lupus Erythematous. I) A multi-system, multifactorial, autoimmune disorder characterised by the development of auto- antibodies directed against various self-antigens. Systemic lupus erythe-matosus will be restricted to those forms of systemic lupus erythematosus which involve the kidneys (Class III to Class V lupus nephritis, established by renal biopsy, and in accordance with the World Health Organization (WHO) classification). The final diagnosis must be confirmed by a registered Medical Practitioner specialising in Rheumatology and Immunology acceptable to Us, Other forms, discoid lupus, and those forms with only haematological and joint involvement are however not covered: The WHO lupus classification is as follows:
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Systemic Lupus Erythematous. A multi-system, multifactorial, autoimmune disorder characterised by the development of auto-antibodies directed against various self- antigens. Only those forms of systemic lupus erythematous which involve the kidneys (Class III to Class V lupus nephritis, established by renal biopsy, and in accordance with the World Health Organization (WHO) classification) will be covered by Us under this Section. The final diagnosis must be confirmed by a registered Medical Practitioner specialising in Rheumatology and Immunology acceptable to Us. Other forms of systemic lupus erythematous, discoid lupus and those forms with only haematological and joint involvement are however not covered: The WHO lupus classification is as follows: • Class I: Minimal change - Negative, normal urine. • Class II: Mesangial - Moderate proteinuria, active sediment. • Class III: Focal Segmental - Proteinuria, active sediment. • Class IV: Diffuse - Acute nephritis with active sediment and/or nephritic syndrome. • Class V: Membranous - Nephrotic Syndrome or severe proteinuria.
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