Bispecific Antibody definition

Bispecific Antibody means a single molecular entity comprising two separate Antibodies, each of which is Directed To a different single Target (and for clarity, no additional Targets).

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Bispecific Antibody means a single molecular entity that is comprised of (a) [***], and (b) [***].

Bispecific Antibody means an Antibody comprising antigen-binding sites of two different monoclonal Antibodies. The term Bispecific Antibody further includes the subtypes of [***] Antibodies having additional binding affinities to antigens or cells expressing such antigens.

Examples of Bispecific Antibody in a sentence

Notwithstanding the above Genmab shall still be entitled to develop and commercialize such Antibody under the applicable license granted herein as a component of a Bispecific Antibody, provided Genmab notifies Medarex of this, [***], prior to the expiration of the time period in Section 7.3, in which case Section 7.3(d) shall apply.
In the event Medarex indicates to Genmab that a given Antibody or a given Bispecific Antibody is available, then such Antibody or such Bispecific Antibody will automatically be deemed to be irrevocably included in such Exclusive Antibody License.
In order to determine whether or not a specific Antibody or a specific Bispecific Antibody is available for inclusion in a particular Exclusive Antibody License, Medarex and Genmab shall follow the procedure set forth in this Section 16.2.2A.
In the event Medarex indicates to Genmab that a given Antibody or a given Bispecific Antibody is unavailable, [***].
Any optimization, Development, Manufacturing, and/or Commercialization of the applicable Unilateral Bispecific Antibody and Unilateral Product under a Unilateral Program shall be at the Unilateral Party’s sole cost and expense.
Under the Research Program, the Parties will collaborate, with each Party applying its own proprietary technologies, to generate Collaboration Bispecific Antibodies and evaluate such constructs against the Evaluation Criteria, which constructs, if determined by the JRC to have achieved the Evaluation Criteria, shall thereafter be considered to be an Evaluated Bispecific Antibody.
For each Evaluated Bispecific Antibody, each Party shall have the right to conduct further Development (“Opt-In Right”), including generating an optimized version of such Evaluated Bispecific Antibody suitable for IND-enabling studies (each, an “Optimized Bispecific Antibody”).
From time to time during the Fc Target Selection Period, Novartis may submit to the Fc Gatekeeper a written notice (the “Fc Notice”) identifying a Target (including a Target that would be Specifically Bound by a Bispecific Antibody) that it wishes to designate as a Fc Target for the purposes of this Agreement (each, a “Proposed Fc Target”).
The Unilateral Party shall have sole decision-making authority with respect to the optimization of the Evaluated Bispecific Antibody, and further Development and Commercialization of any resulting Unilateral Bispecific Antibody or Unilateral Product within a Unilateral Program.
A Party may exercise its Opt-In Right for an Evaluated Bispecific Antibody at any time during the Opt-In Term by giving written notice to the other Party.

More Definitions of Bispecific Antibody

Bispecific Antibody means any Antibody that contains independent binding sites Directed To […***…].

Bispecific Antibody means Bispecific One Target Antibody and Bispecific Two Target Antibody. For the purpose of this Agreement, a Bispecific Antibody shall be defined by [***]. Furthermore, a Bispecific Antibody which has [***] shall be considered different from such. In addition, a Bispecific Antibody which has [***] shall be considered different from such [***].

Bispecific Antibody means a human bispecific antibody that (a) binds specifically to the Virus, (b) is generated by using two Antibodies, that each bind to a different antigen target, or different epitopes on the same target, and (c) has anti-viral activity in preclinical studies based on well-established methods.

Bispecific Antibody means an Antibody that includes the CDRs from two different parental Antibodies. A Bispecific Antibody comprises two active components.

Bispecific Antibody means [***];