Bispecific Antibody definition

Bispecific Antibody means an Antibody comprising antigen-binding sites of two different monoclonal Antibodies. The term Bispecific Antibody further includes the subtypes of [***] Antibodies having additional binding affinities to antigens or cells expressing such antigens.
Sample 1Sample 2
Bispecific Antibody means any Antibody that contains independent binding sites Directed To […***…].
Sample 1Sample 2Sample 3
Bispecific Antibody means any Antibody that contains independent binding sites Directed To two (2) Targets or two (2) epitopes on one (1) Target.
Sample 1

Examples of Bispecific Antibody in a sentence

  • David Gruber1, Mikhail Kozlov2, Romas Skudas3, 1MedImmune Ltd, Cambridge, Cambridgeshire, UK; 2EMD Millipore, Bedford, MA, USA; 3EMD Millipore, Darmstadt, Hessen, GERMANY 4:20 PM Purification of a Common Light Chain Bispecific Antibody using Contichrom (MCSGP).

  • The Bispecific Antibody Product enjoys the advantages of high affinity, strong inhibitory activity, high preparation concentration, good stability and low dosing frequency.

  • VEGF/ANG2 Tetravalent Bispecific Antibody Product is a class I innovative biological product with a unique nanobody design for treatment of ocular fundus neovascular diseases, targeting VEGF (vascular endothelial growth factor) and ANG2 (angiopoietin 2), which effectively inhibits abnormal neovascularization and is in the preclinical stage.

  • In order to determine whether or not a specific Antibody or a specific Bispecific Antibody is available for inclusion in a particular Exclusive Antibody License, Medarex and Genmab shall follow the procedure set forth in this Section 16.2.2A.

  • Notwithstanding the above Genmab shall still be entitled to develop and commercialize such Antibody under the applicable license granted herein as a component of a Bispecific Antibody, provided Genmab notifies Medarex of this, [***], prior to the expiration of the time period in Section 7.3, in which case Section 7.3(d) shall apply.

  • Multiple Doses of an Anti-FGFR1/ KLB Bispecific Antibody (BFKB8488A) are Associated with a Decrease in Hepatic Fat in Patients with NAFLD.

  • In the event Medarex indicates to Genmab that a given Antibody or a given Bispecific Antibody is available, then such Antibody or such Bispecific Antibody will automatically be deemed to be irrevocably included in such Exclusive Antibody License.

  • In the event Medarex indicates to Genmab that a given Antibody or a given Bispecific Antibody is unavailable, [***].

  • The Bispecific Antibody Product will enrich the Group’s innovative pipeline in the ocular fundus diseases treatment field, enhancing the competitiveness of the ophthalmology business.

  • For each Joint Program, either Party may recommend to the other Party, at any time, Out-Licensing Commercialization rights (and optionally, Development rights) relating to the applicable Joint Bispecific Antibody and Joint Product in the Field, either in the Territory or in select countries, to a Third Party; provided, that the Lead Party shall have the [*] right to decide whether to pursue such an Out-Licensing approach.


More Definitions of Bispecific Antibody

Bispecific Antibody means a molecule, or a covalently linked plurality of molecules, which comprise(s) two (2) different [******], one of which [******] and the other of which [******].
Sample 1
Bispecific Antibody means Bispecific One Target Antibody and Bispecific Two Target Antibody. For the purpose of this Agreement, a Bispecific Antibody shall be defined by [***]. Furthermore, [***]. In addition, [***].
Sample 1
Bispecific Antibody means an Antibody that includes the CDRs from two different parental Antibodies. A Bispecific Antibody comprises two active components.
Sample 1
Bispecific Antibody means [***];
Sample 1
Bispecific Antibody means a human bispecific antibody that (a) binds specifically to the Virus, (b) is generated by using two Antibodies, that each bind to a different antigen target, or different epitopes on the same target, and (c) has anti-viral activity in preclinical studies based on well-established methods.
Sample 1

Related to Bispecific Antibody

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications, or derivatives thereof, but excluding single variable domains (heavy or light) of such antibodies.

  • Licensed Compound means a TAK-385 Licensed Compound or a TAK-448 Licensed Compound.

  • Collaboration Compound means any of the following: (a) FG-4592, (b) any HIF Compound (other than FG-4592) that is added to this Agreement pursuant to Section 3.6, and (c) any salts, esters, complexes, chelates, crystalline and amorphous morphic forms, pegylated forms, enantiomers (excluding regioisomers), prodrugs, solvates, metabolites and catabolites of any of the foregoing ((a) or (b)).

  • Licensed Compounds means: (a) Research Program Active Compounds; (b) Novartis Active Compounds; (c) salts, hydrates, solvates, esters, metabolites, intermediates, stereoisomers and polymorphs of Research Program Active Compounds or Novartis Active Compounds; and (d) prodrugs of Research Program Active Compounds or Novartis Active Compounds (any of the foregoing, a “Licensed Compound”).

  • Collaboration Product means any pharmaceutical product in finished form that contains a Collaboration Compound, either as the sole active ingredient or in combination with one or more other active ingredients, and all present and future formulations, dosages and dosage forms thereof.

  • Compound means the taking of two or more ingredients and fabricating them into a single

  • Biosimilar means a biological product that is highly similar to a specific reference biological

  • Licensed Product means any pharmaceutical product containing a Licensed Compound (alone or with other active ingredients), in all forms, presentations, formulations and dosage forms.

  • Collaboration Target means the Initial Collaboration Targets set forth on Exhibit F and any Additional Target or Substitute Target that is selected in accordance with Section 3.3 of this Agreement.

  • Combination Product means a product (a) containing a Licensed Product together with one or more other active ingredients, or (b) with one or more products, devices, pieces of equipment or components, but sold for an integrated price (e.g., with the purchase of one product the customer gets a coupon for the other) or for a single price.

Most Referenced Clauses

Most Referenced Definitions