Method validation definition

Method validation means the process of demonstrating or con- firming that a method is suitable for its intended purpose. Validation criteria include demonstrating performance characteristics such as ac- curacy, precision, selectivity, limit of detection, limit of quantita- tion, linearity, range, ruggedness, and robustness.
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Examples of Method validation in a sentence

  • Analytical Method validation and Instrument Performance Verification by Churg Chan, Heiman Lam, Y.C. Lee, Yue.

  • Method validation and quality control procedures for pesticide residues analysis in food and feed.

  • Method validation for SNPs embedded in arbitrary matrices In order to prove the versatility of the DdD method, it was applied to other systems taken from literature data: CdS and other SNPs, such as CdSe, included in diverse media (liquid, so or solid).

  • Method validation procedures were based on relevant guidelines (Green et al., 1996, Shah et al., 2000).

  • Method validation at Tier 2 consists of running tests on a single matrix type collected from three different facilities in the same industrial subcategory, with the sample being analyzed in three separate laboratories (see 40 CFR parts 405 - 503 for industrial categories and subcategories).

  • Method validation is one of several important quality system components that are designed to ensure the production of scientifically valid and useful analytical data (2).

  • Method validation studies may involve a single laboratory (intralaboratory) or multiple laboratories (interlaboratory).

  • Method validation and measurement of biomarkers in nonclinical and clinical samples in drug development: a conference report.

  • Method validation at Tier 1 consists of (1) using the new method to perform an MDL study in accordance with the MDL procedure described at 40 CFR part 136, Appendix B, (2) using the results of this MDL study to establish an ML, and (3) running, in a single laboratory, a test of four spiked reference matrix samples and four spiked samples of the sample matrix (or matrices) to which the method is to be applied.

  • Method validation is the process used to confirm that the analytical procedure employed for a specific test is suitable for its intended use.

Related to Method validation

  • Validation as used in WAC 222-20-016, means the department's agreement that a small forest landowner has correctly identified and classified resources, and satisfactorily completed a roads assessment for the geographic area described in Step 1 of a long-term application.

  • Inpatient treatment means twenty-four-hour-per-day mental

  • method of polling means a method of casting a vote in a poll, which may be by post, internet, text message or telephone;

  • Genetic testing means an analysis of genetic markers to exclude or identify a man as the father or a woman as the mother of a child. The term includes an analysis of one or a combination of the following:

  • traceability means the ability to trace and follow a food, feed, food-producing animal or substance intended to be, or expected to be incorporated into a food or feed, through all stages of production, processing and distribution;

  • Nonambulatory means a person who immediately and without the aid of another is not physically and mentally capable of traveling a normal path to safety, including the ascent and descent of stairs.

  • Outpatient treatment means mental health or substance abuse treatment services rendered to a

  • Standard Methods for the Examination of Water and Wastewater means the most recent edition of Standard Methods for the Examination of Water and Wastewater published jointly by the American Public Health Association, the American Waterworks Association and the Water Environment Federation;

  • Assisted outpatient treatment or "AOT" means the categories of outpatient services ordered by the court under section 468 or 469a. Assisted outpatient treatment may include a case management plan and case management services to provide care coordination under the supervision of a psychiatrist and developed in accordance with person-centered planning under section 712. Assisted outpatient treatment may also include 1 or more of the following categories of services: medication; periodic blood tests or urinalysis to determine compliance with prescribed medications; individual or group therapy; day or partial day programming activities; vocational, educational, or self-help training or activities; assertive community treatment team services; alcohol or substance use disorder treatment and counseling and periodic tests for the presence of alcohol or illegal drugs for an individual with a history of alcohol abuse or substance use disorder; supervision of living arrangements; and any other services within a local or unified services plan developed under this act that are prescribed to treat the individual's mental illness and to assist the individual in living and functioning in the community or to attempt to prevent a relapse or deterioration that may reasonably be predicted to result in suicide, the need for hospitalization, or serious violent behavior. The medical review and direction included in an assisted outpatient treatment plan shall be provided under the supervision of a psychiatrist.

  • Process Wastewater means any water which, during manufacturing or processing, comes into direct contact with or results from the production or use of any raw material, intermediate product, finished product, by-product, or waste product.

  • Scaling as used herein, involves:

  • Acceptance Testing mean the tests, reviews and other activities that are performed by or on behalf of Agency to determine whether the Deliverables meet the Acceptance Criteria or otherwise satisfy the Agency, as determined by the Agency in its sole discretion.

  • Architectural coating means a coating applied to stationary structures and their appurtenances, to mobile homes, to pavements, or to curbs.

  • Permeability of a space means the ratio of the volume within that space which is assumed to be occupied by water to the total volume of that space.

  • Detoxification means a process whereby an alcohol or drug intoxicated, or alcohol or drug dependent, individual is assisted through the period of time necessary to eliminate, by metabolic or other means, the intoxicating alcohol or drug, alcohol or drug dependent factors, or alcohol in combination with drugs, as determined by a licensed Health Professional, while keeping the physiological risk to the individual at a minimum.

  • Serialization within the part, lot, or batch number means each item of a particular part, lot, or batch number is assigned a unique serial number within that part, lot, or batch number assignment. The enterprise is responsible for ensuring unique serialization within the part, lot, or batch number within the enterprise identifier.

  • Certified components means components of X-ray systems which are subject to regulations promulgated under Public Law 90-602, the “Radiation Control for Health and Safety Act of 1968,” the Food and Drug Administration.

  • Fluoroscopic imaging assembly means a subsystem in which X-ray photons produce a visual image. It includes the image receptor(s) such as the image intensifier and spot-film device, electrical interlocks, if any, and structural material providing linkage between the image receptor and diagnostic source assembly.

  • Testing means that element of inspection that determines the properties or elements, including functional operation of materials, equipment, or their components, by the application of established scientific principles and procedures.

  • Containment means a process to protect workers and the environment by controlling exposures to the lead-contaminated dust and debris created during an abatement.

  • Medication-assisted treatment or "MAT" means the use of pharmacologic therapy, often in combination with counseling and behav- ioral therapies, for the treatment of substance use disorders.

  • Interoperability means the ability of a CenturyLink OSS Function to process seamlessly (i.e., without any manual intervention) business transactions with CLEC's OSS application, and vice versa, by means of secure exchange of transaction data models that use data fields and usage rules that can be received and processed by the other Party to achieve the intended OSS Function and related response. (See also Electronic Bonding.)