Method validation definition

Method validation means the process of demonstrating or con- firming that a method is suitable for its intended purpose. Validation criteria include demonstrating performance characteristics such as ac- curacy, precision, selectivity, limit of detection, limit of quantita- tion, linearity, range, ruggedness, and robustness.
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Examples of Method validation in a sentence

  • Analytical Method validation and Instrument Performance Verification by Churg Chan, Heiman Lam, Y.C. Lee, Yue.

  • Method validation and quality control procedures for pesticide residues analysis in food and feed.

  • Method validation for SNPs embedded in arbitrary matrices In order to prove the versatility of the DdD method, it was applied to other systems taken from literature data: CdS and other SNPs, such as CdSe, included in diverse media (liquid, so or solid).

  • Method validation procedures were based on relevant guidelines (Green et al., 1996, Shah et al., 2000).

  • Method validation at Tier 2 consists of running tests on a single matrix type collected from three different facilities in the same industrial subcategory, with the sample being analyzed in three separate laboratories (see 40 CFR parts 405 - 503 for industrial categories and subcategories).

  • Method validation is one of several important quality system components that are designed to ensure the production of scientifically valid and useful analytical data (2).

  • Method validation studies may involve a single laboratory (intralaboratory) or multiple laboratories (interlaboratory).

  • Method validation and measurement of biomarkers in nonclinical and clinical samples in drug development: a conference report.

  • Method validation at Tier 1 consists of (1) using the new method to perform an MDL study in accordance with the MDL procedure described at 40 CFR part 136, Appendix B, (2) using the results of this MDL study to establish an ML, and (3) running, in a single laboratory, a test of four spiked reference matrix samples and four spiked samples of the sample matrix (or matrices) to which the method is to be applied.

  • Method validation is the process used to confirm that the analytical procedure employed for a specific test is suitable for its intended use.

Related to Method validation

  • Validation as used in WAC 222-20-016, means the department's agreement that a small forest landowner has correctly identified and classified resources, and satisfactorily completed a roads assessment for the geographic area described in Step 1 of a long-term application.

  • traceability means the ability to trace and follow a food, feed, food-producing animal or substance intended to be, or expected to be incorporated into a food or feed, through all stages of production, processing and distribution;

  • Outpatient treatment means any of the nonresidential

  • Detoxification means a process whereby an alcohol or drug intoxicated, or alcohol or drug dependent, individual is assisted through the period of time necessary to eliminate, by metabolic or other means, the intoxicating alcohol or drug, alcohol or drug dependent factors, or alcohol in combination with drugs, as determined by a licensed Health Professional, while keeping the physiological risk to the individual at a minimum.

  • Serialization within the part, lot, or batch number means each item of a particular part, lot, or batch number is assigned a unique serial number within that part, lot, or batch number assignment. The enterprise is responsible for ensuring unique serialization within the part, lot, or batch number within the enterprise identifier.

  • Containment means the installation of a backflow prevention assembly or a backflow prevention method at any connection to the public water system that supplies an auxiliary water system, location, facility, or area such that backflow from a cross connection into the public water system is prevented.

  • Interoperability means the ability of a CenturyLink OSS Function to process seamlessly (i.e., without any manual intervention) business transactions with CLEC's OSS application, and vice versa, by means of secure exchange of transaction data models that use data fields and usage rules that can be received and processed by the other Party to achieve the intended OSS Function and related response. (See also Electronic Bonding.)