Biotransformation. Appropriate qualitative and quan- titative methods shall be used to assay urine, feces, and expired air collected from rats. Efforts shall be made to identify any metabolite which com- prises 5 percent or more of the adminis- tered dose and the major radioactive components of blood.
Biotransformation. Appropriate qualitative and quantitative methods shall be used to assay urine, feces, and expired air collected from rats. Efforts shall be made to identify any metabo- lite which comprises 5 percent or more of the dose administered.
Biotransformation. App r op r i a t e q u a li t a t ive a n d q u a n- t i t a t ive m e t h ods s h a ll be u sed t o a ss a y ur i n e, feces, a n d expi r ed a i r collec t ed f r o m r a t s. Effo r t s s h a ll be m a de t o ide n t ify a ny m e t a boli t e w h ic h co m - p r i ses 5 pe r ce n t o r m o r e of t h e a d m i n i s- t e r ed dose a n d t h e m a jo r r a dio a c t ive co m po n e n t s of blood.
