Common use of Date of Application Clause in Contracts

Date of Application. None The Grantor has granted Secured Party certain licenses to the Intellectual Property pursuant to the Concurrent Agreements. The Grantor is a party to the JHU Agreements. Pursuant to the JHU Agreements, JHU has the retained right to make, have made, provide and use for its and The Xxxxx Xxxxxxx Health Systems’ internal, non-commercial purposes “Licensed Products” and “Licensed Services” (as such terms are defined in the JHU Agreements). Patents supported by federal funding are subject to the rights, conditions and limitations imposed by U.S. law. The Grantor is a party to an option agreement with JHU. Pursuant to that option agreement, the Grantor has notified JHU that the Grantor will exercise its option on a “Microcapsule” patent application that was filed in May 2007. Such patent application is not related to the Lead or the System. The Grantor is a party to an assignment agreement with [***] for [***]. The Grantor has a pending research collaboration/sponsorship agreement with UCSF. The Grantor has a pending sponsorship agreement with the University of Utah and Xx. Xxxxxxxxx (with an option for an exclusive license for any intellectual property arising from the sponsored work). Such intellectual property would not be related to the Lead or the System. The Grantor has filed on a JHU case (funded by the Grantor) that has not yet been formally licensed from JHU. The case is directed to embolic procedures and is not related to the Lead or the System. The Grantor is a party to various consulting agreements that include options/licenses/assignments of or to intellectual property or conceived ideas. The Grantor knows of a third-party attempt to invoke an interference against U.S. 6,904,307. [***] Indicates portions of this exhibit that have been omitted and filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment.

Date of Application. None The Grantor has granted Secured Party certain licenses to the Intellectual Property pursuant to the Concurrent Agreements. The Grantor is a party to the JHU Agreements. Pursuant to the JHU Agreements, JHU has the retained right to make, have made, provide and use for its and The Xxxxx Xxxxxxx Health Systems’ internal, non-commercial purposes “Licensed Products” and “Licensed Services” (as such terms are defined in the JHU Agreements). Patents supported by federal funding are subject to the rights, conditions and limitations imposed by U.S. law. The Grantor is a party to an option agreement with JHU. Pursuant to that option agreement, the Grantor has notified JHU that the Grantor will exercise its option on a “Microcapsule” patent application that was filed in May 2007. Such patent application is not related to the Lead or the System. The Grantor is a party to an assignment agreement with [***] for [***]. The Grantor has a pending research collaboration/sponsorship agreement with UCSF. The Grantor has a pending sponsorship agreement with the University of Utah and Xx. Xxxxxxxxx (with an option for an exclusive license for any intellectual property arising from the sponsored work). Such intellectual property would not be related to the Lead or the System. The Grantor has filed on a JHU case (funded by the Grantor) that has not yet been formally licensed from JHU. The case is directed to embolic procedures and is not related to the Lead or the System. The Grantor is a party to various consulting agreements that include options/licenses/assignments of or to intellectual property or conceived ideas. The Grantor knows of a third-party attempt to invoke an interference against U.S. 6,904,307. [***] [***] Indicates portions of this exhibit that have been omitted and filed separately with the Securities and Exchange Commission pursuant to a request for confidential treatment.