THE THIRD SUPPLEMENTAL AGREEMENT Clause Samples

THE THIRD SUPPLEMENTAL AGREEMENT. Under the Third Supplemental Agreement, Zhenjiang Committee undertakes to provide Genscript HK the Total Reserved Land (as defined below) for, in addition to the purposes stipulated in the Announcements, bio-related projects (details being subject to project feasibility studies to be performed). The major terms of the Third Supplemental Agreement are set out as below: Total Reserved Land: The total area of the Phase II Land and Further Reserved Land shall now be amended as a total area of 300 Mu (the “Total Reserved Land”). Registered capital: The registered capital of the relevant project company, being a wholly-owned subsidiary of the Company to be identified, shall be increased by US$60,000,000. Commencement of investment: Genscript HK undertakes to commence the construction on or before 31 December 2020. Zhenjiang Committee undertakes to reserve the Total Reserved Land until 31 December 2020. Scope of business: Bio-related projects (details being subject to project feasibility studies to be performed). Subsidies will, in principle, be similar to those under the Investment Agreement, First Supplemental Agreement and Second Supplemental Agreement. However, they are subject to separate negotiation and execution of a further supplemental agreement by and between Zhenjiang Committee and Genscript HK. Housing allowances Zhenjiang Committee will set up a housing incentive fund for the employees of the relevant project company who purchase properties in the Zhenjiang New Area and fulfil all the other conditions stipulated in a separate specific incentive plan that will be formulated by Genscript HK and be subject to the review and approval of Zhenjiang Committee. Equipment subsidies Zhenjiang Committee shall provide the Project Company with a subsidy equivalent to no more than 30% of the amount incurred by the relevant project company for purchasing research and development equipment in the year preceding, subject to other terms and conditions. On the signing date of the Third Supplemental Agreement, provisions that have not yet been fulfilled under the following headings of the announcement of the Company dated 20 June 2016 in relation to the Investment Agreement will no longer be in force: • “Phase I – Subsidies by the Zhenjiang Committee – Research and Development center”; • “Phase II – Subsidies by the Zhenjiang Committee – Equipment subsidies”; • “Phase II – Subsidies by the Zhenjiang Committee – High-end talents support funds”; and • “New Projects”. On t...

THE THIRD SUPPLEMENTAL AGREEMENT. On 9 October 2015, the Vendor, the Purchaser and the Vendor’s Guarantor entered into the Third Supplemental Agreement to further amend the terms of the Sale and Purchase Agreement, pursuant to which the parties agreed that, among others:

THE THIRD SUPPLEMENTAL AGREEMENT. The Board announces that on 27 September 2017 (after trading hours), the Lender, the Borrower and the Guarantor entered into a third supplemental agreement (the “Third Supplemental Agreement”) pursuant to which the parties agreed to further extend the repayment date under the Loan Agreement (as supplemented and amended by the Supplemental Agreement and the Second Supplemental Agreement) from 27 September 2017 to 27 October 2017. The terms of the Third Supplemental Agreement were arrived between the parties after arm’s length negotiation. As the Lender will continue to receive interest income from the Borrower for the extension period, the Directors consider that the above- mentioned amendments to the Loan Agreement are fair and reasonable and are in the interests of the Company and its shareholders as a whole. Save as amended by the Third Supplemental Agreement, all other terms and conditions of the Loan Agreement (as supplemented and amended by the Supplemental Agreement and the Second Supplemental Agreement) remain unchanged. Hong Kong, 27 September 2017

THE THIRD SUPPLEMENTAL AGREEMENT. On 21 January 2014, the Lender entered into a third supplemental agreement (the “Third Supplemental Agreement”) with the Borrower and T & M Holdings, pursuant to which the Lender agreed to further extend the repayment date under the Loan Agreement as amended by the Supplemental Agreement and the Second Supplemental Agreement from 10 January 2014 to 10 July 2014. The terms of the Third Supplemental Agreement were arrived between the parties after arm’s length negotiation.

THE THIRD SUPPLEMENTAL AGREEMENT. On 23 April 2019 (after trading hours), the Company, the Purchaser and the Vendor entered into a third supplemental agreement (the “Third Supplemental Agreement”) to the SPA (as supplemented by the First Supplemental Agreement and the Second Supplemental Agreement) with a view to amending the time for payment of the Last Payment such that it shall be payable by the Purchaser as to (a) RMB3,795,000 (equivalent to approximately HK$4,424,000) by set-off against the Leasing Deposit; and