Lead Molecule definition

Lead Molecule means a Collaboration Molecule that satisfies the Lead Criteria as determined by the Program Committee and confirmed by JBI acting in good faith.
Sample 1Sample 2Sample 3
Lead Molecule means, with respect to an Approved Collaboration Target, the lead Small Molecule arising out of the Research Program directed to that Approved Collaboration Target.
Sample 1Sample 2
Lead Molecule means that certain Collaboration Molecule incorporated in the first Licensed Product to receive IND approval and/or complete a Phase I Clinical Trial.
Sample 1Sample 2

Examples of Lead Molecule in a sentence

  • Regardless of the Progression ---------------------------------- Strategy agreed upon pursuant to Section 5.1 above, at any time a party determines that a Lead Molecule has developed into a Candidate Compound, such party shall promptly notify the P.12 other party and within 90 days of such notice the parties shall attempt to agree upon the Development Strategy to be employed with respect to such Candidate Compound.

  • If Licensee exercises the Back-up Option prior to the delivery by Kxxxxx to Licensee of the Phase I Data Package for the Lead Molecule and then subsequently elects to exercise the Lead Option, Licensee shall pay to Kineta the difference between the Option Exercise Payment for the Lead Option and the Back-up Option or [***].

  • For clarity, JBI shall not have a license from Scholar Rock to Commercialize any Collaboration Molecule, Lead Molecule or Licensed Product unless and until JBI has exercised its License Option in accordance with Section 2.2 for Collaboration Molecules with such Pharmacological Profile.

  • On a Pharmacological Profile-by-Pharmacological Profile basis, Scholar Rock will notify the Program Committee upon designating that a Collaboration Molecule should be a Lead Molecule for such Pharmacological Profile based upon satisfaction of the Lead Criteria.

  • In the event the parties agree to proceed with the ---------------------------- Development of one or more Candidate Compounds pursuant to Section 5.2 (i) or Section 5.2 (ii) above, the party responsible for Progression of the chosen Candidate Compounds from a Lead Molecule will be reimbursed 50% of its total, fairly allocated costs incurred during such Progression by the other party, including but not limited to costs incurred related to support provided by the other party during such Progression.

  • ALL SUCH OMITTED MATERIAL HAS BEEN FILED WITH THE SECURITIES AND EXCHANGE COMMISSION PURSUANT TO RULE 406 PROMULGATED UNDER THE SECURITIES ACT OF 1933, AS AMENDED Scholar Rock or its Affiliate or sublicensee on all sales of such Licensed Product(s) or products incorporating the same Collaboration Molecule or Lead Molecule as a terminated Licensed Product (collectively “Returned Product”).

  • In the event that the Program Committee’s and JBI’s assessment is that such Lead Molecule fulfills the Lead Criteria, JBI shall so notify Scholar Rock on or [***] INDICATES MATERIAL THAT HAS BEEN OMITTED AND FOR WHICH CONFIDENTIAL TREATMENT HAS BEEN REQUESTED.

  • Other representatives of each Party involved with the Collaboration Molecule, Lead Molecule or Licensed Product may attend meetings as non-voting participants, subject to the confidentiality provisions set forth in ARTICLE 10.

  • The following restrictions shall apply on a Pharmacological Profile-by-Pharmacological Profile basis with respect to any academic, scientific, medical or other publication or presentation or other disclosure by Scholar Rock or JBI that contains or refers to or otherwise relates to any Collaboration Molecule, Lead Molecule or Licensed Product prior to exercise of the License Option for such Pharmacological Profile.

  • In the event that, following Deconvolution, a Lead Extract is determined not to contain a Lead Molecule or if, after reasonable effort a Lead Molecule cannot be deconvoluted, or in the event a Lead Extract has not entered into Deconvolution within [ ]* of designation by the Committee as a Lead Extract, any encumbrances placed upon Phytera's use of such Lead Extract outside this Agreement shall lapse and Phytera shall be free to use the Lead Extract in other research programs.


More Definitions of Lead Molecule

Lead Molecule means the molecule comprised of an Active Moiety and a single XTEN Sequence that is set forth on Exhibit B or such Backup Molecule that may become the Lead Molecule as set forth in Section 2.3.
Sample 1Sample 2
Lead Molecule means the specific chemical entity responsible for ------------- identified Requisite Activity in a Lead Extract and/or any analogs, derivatives and homologs of such a specific chemical entity which are synthesized, identified or produced on the basis of such specific chemical entity or Lead Molecule derived above.
Sample 1Sample 2
Lead Molecule means (a) XTX301 [**] and (b) any IL-12 Molecule that [**]. For clarity, [**].
Sample 1
Lead Molecule means birinapant or SHP-141 (remetinostat) (together, the “Lead Molecules”).
Sample 1

Related to Lead Molecule

  • Licensed Compound means (a) 3,4-Diaminopyridine, the chemical structure of which is set forth on Exhibit B-2; and (b) any derivatives, isomers, metabolites, prodrugs, acid forms, base forms, salt forms, or modified versions of such compound in (a).

  • Compound means the taking of two or more ingredients and fabricating them into a single

  • Licensed Compounds means any EZH2 Compound(s) that is:

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Diagnostic Product means In Vitro Diagnostics, In Vivo Diagnostic Agents and any other aptamer product used for Diagnosis. For purposes of clarity, the term Diagnostic Product shall not include a product used for the delay of onset or progression of, or treatment or prevention of, an Indication.

  • Collaboration Target means the Initial Collaboration Targets set forth on Exhibit F and any Additional Target or Substitute Target that is selected in accordance with Section 3.3 of this Agreement.

  • Compounds means a small molecule HMT inhibitor.

  • Exempt compound means the same as defined in Rule 2.

  • Biomarker means a parameter or characteristic in a patient or Patient Sample, the measurement of which is useful (a) for purposes of selecting appropriate therapies or patient populations or monitoring disease susceptibility, severity or state, or monitoring therapies for such patient and/or (b) for predicting the outcome of a particular treatment of such patient.

  • Therapeutic diet means meals served that are soft, low-fat, low-sodium or controlled calorie.

  • Active Pharmaceutical Ingredient or “API” shall mean one or more of the following active pharmaceutical ingredients: tenofovir alafenamide (“TAF”), tenofovir disoproxil fumarate (“TDF”), elvitegravir (“EVG”), and cobicistat (“COBI”).

  • Nicotine product means a product that contains nicotine and is not any of the following:

  • Drug Substance means an active ingredient that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient.

  • medicinal product means any substance or combination of substances presented for treating or preventing disease in human beings or animals and any substance or combination of substances which may be administered to human beings or animals with a view to making a medical diagnosis or to restoring, correcting or modifying physiological functions in humans or in animals;

  • Companion Diagnostic means a device which is essential for the safe and effective use of a corresponding medicinal product to:

  • Licensed Product means any method, process, composition, product, service, or component part thereof that would, but for the granting of the rights set forth in this Agreement, infringe a Valid Claim contained in the Licensed Patents.

  • Biological product means a virus, therapeutic serum, toxin, antitoxin, vaccine, blood, blood component or derivative, allergenic product, protein other than a chemically synthesized polypeptide, or analogous product, or arsphenamine or any derivative of arsphenamine or any other trivalent organic arsenic compound, applicable to the prevention, treatment, or cure of a disease or condition of human beings.