BAC. In addition, an employee with an alcohol concentration of 0.02 or greater, but less than 0.04, will not be permitted to drive a commercial motor vehicle for a minimum of 24 hours.
BAC. An employee who has tested at or above 0.02 BAC but less than 0.04 SAC, and who subsequently tests at or above 0.02 on a second occasion, shall be subject to the same treatment as an employee testing at or above 0.04
BAC. Note: The terms “buyer,” “seller,” “agreement of sale,” and “purchase” also will be construed to mean “tenant,” “landlord,” “lease,” and “rent,” respectively, throughout this agreement.
BAC. If an employee's BAC is determined to be between .02% and .039% by testing with the EBT device, the employee shall not be permitted to operate any Township vehicle or equipment for twenty-four (24) hours from the time the test was taken.
BAC. Dynex and Guarantor have requested and hereby consent to the termination of MHFC as a Seller under the Repurchase Agreement.
BAC and Dynex hereby ratify and confirm that, except as modified and amended by this Amendment, the Repurchase Agreement, and all other agreements and instruments executed and/or delivered thereunder by either or both of them to or for the benefit of the Buyer, remain in full force and effect in accordance with their respective terms.
BAC. BAC is an existing corporation duly organized and in good --- standing under the laws of the State of Delaware, with its principal executive offices located in San Francisco, California.
BAC. BAC is a workflow tool that runs and analyses simulations designed to assess how well drugs bind to their target proteins and the impact of changes to those proteins. It provides a collection of scripts, which wrap around common molecular dynamics codes to facilitate free energy calculations. BAC is being used as a clinical decision support tool with a clear aim of clinically driven research, and there is considerable hope to take this further in the future. BAC delivers the use of ensemble simulations to provide robust, accurate and precise free energy computations from both alchemical and end-point analysis methodologies. EnsembleMD [31] are commercially developing user friendly interfaces to replace existing prototypes produced at UCL. Non-clinical research ✔ Clinical research ✔ Clinical decision support ✔ Drug discovery ✔ Design & optimisation ✔ Personal health forecasting Contact email: xxxx.xxxxxx@xxx.xx.xx End user name Xxx Xxxx Xxxxxxx xxx Xxxxxxx Xxxxx X. Xxxxxxx’x group Affiliation GSK Xxxxxxx UCL Application area Drug discovery Drug discovery Clinical decision support and drug design No. of associated users 2 5 10 Target use Commercial / research Commercial Research Improvements implemented Initial web interface (UF-BAC) developed to facilitate usage, workflow deployed on DNAnexus cloud Azure deployment and extension of UF- BAC interface None Impact Clinical validation Use of any e- infrastructure available via CompBioMed Compute time at BSC and Cirrus at EPCC (testing of container based solution) Compute time at SURFsara Compute time at SURFsara, BSC, EPCC
BAC. The Binding Affinity Calculator (BAC) is a workflow tool that analyses simulations designed to assess how well drugs bind to their target proteins and the impact of changes to those proteins. It is a collection of scripts which wrap around common molecular dynamics codes to facilitate free energy calculations. Use of ensemble simulations to robust, accurate and precise free energy computations from both alchemical and end-point analysis methodologies. BAC is a fairly complex tool to use, so at the moment the development team at UCL have made it available as part of consulting services or research collaborations. However, EnsembleMD provides user- friendly interfaces to related binding affinity calculation services, which will be made available as an App in the on-line store of associate partner DNAnexus; a beta version is being used by pharma. BAC is actively developed and optimised for emerging exascale systems, and the associated optimisation work is detailed in Section 7 of D5.6. NB BAC can employ a number of Molecular Dynamics codes; the main codes in use at this time include NAMD, GROMACS, and OpenMM.
BAC. “BAC” shall have the meaning set forth in the preamble to the Agreement.
