Blocked Targets Sample Clauses

Blocked Targets. (i) From time to time during the term of this Agreement but no more frequently than [**] (except as set forth in clause (ii) of this Section 2.4(a)), following an affirmative decision by Licensee to initiate a program directed to the Discovery, Development or Commercialization of RNAi Compounds directed to a particular Target, Licensee may inquire of the Gatekeeper in writing whether or not such Target is on the Blocked Target List by virtue of being subject to a then-current exclusive or co-exclusive grant, option, right of first refusal or similar right under a Pre-Existing Alliance Agreement. The Gatekeeper shall, within [**] days following the Gatekeeper’s receipt of such complete written request from Licensee, notify Licensee in writing whether or not such Target is on the Blocked Target List; provided, however, that in no event will the Gatekeeper directly or indirectly notify or communicate to any other Alnylam employee or consultant or any Alnylam Affiliate or Third Party the contents or the existence of Licensee’s inquiry hereunder without Licensee’s prior written consent, which may be withheld at Licensee’s sole discretion. (ii) If Alnylam becomes aware of the removal of any Target from the Blocked Target List, Alnylam shall notify Licensee of such removal (but not the identity of the Target which was removed) and Licensee shall have the right to inquire of the Gatekeeper pursuant to, and in compliance with, clause (i) above whether or not a Target is on the Blocked Target List; provided, however, that the [**] limit set forth in clause (i) above on the frequency of inquiries which may be made of the Gatekeeper shall not apply with respect to an inquiry made under this Section 2.4(a)(ii), nor shall an inquiry made under this Section 2.4(a)(ii) be counted towards such [**] limit. (iii) Notwithstanding the foregoing, the Parties acknowledge that a Pre-Existing Alliance Party may subsequently request exclusive or co-exclusive rights from Alnylam with respect to a particular Target as described in Section 2.3(a)(ii) and the provisions of Section 2.3(a)(ii) shall control.

Blocked Targets. Additionally, if during the Target Selection Period, Regulus intends to work outside of the Research Program, along with or for the benefit of an Affiliate, Parent Company or a Third Party, to identify, research, optimize, otherwise Develop or Commercialize any [...***...] prior to the selection by GSK of all four (4) final Collaboration Targets, then Regulus shall first offer in writing to GSK the right to select such xxXXX as one of the remaining Collaboration Targets hereunder, including as a replacement for any Replaceable Target, in each case solely to the extent that GSK has the right to do so under Section 3.2.1 above (including the [...***...] limitation set forth therein), such right to expire [...***...] days after GSK’s receipt of such written offer. If GSK does not select such xxXXX as a Collaboration Target hereunder, such xxXXX shall thereafter be excluded from the xxXXX Pool and deemed a Blocked Target; provided, however, that no more than [...***...] of the number of miRNAs in the xxXXX Pool may be deemed to be a Blocked Target under the Agreement.

Blocked Targets. If the Target nominated by Biogen is not a Reserved Target, then within [*] days after the receipt of the notice from Biogen nominating such Target as a Collaboration Target, Sangamo shall notify Biogen in writing confirming whether (i) [*] with respect to such Target [*] that is [*] and that are [*]; (ii) such Target is [*] and is [*]; or (iii) such Target [*] under which [*] and [*] (each of (i) through (iii), a “Pre-Existing Restriction,” and any such Target described in clauses (i) through (iii), a “Blocked Target”). If the Target nominated by Biogen is a Blocked Target, then Biogen may nominate another Target pursuant to Section 4.7(b) (Blocked Targets) (and another if such new Target is also a Blocked Target, and so on), until such time that Biogen selects a Target that is not a Blocked Target. If at any time during the Target Selection Term, any Pre-Existing Restriction that precluded Biogen from selecting as Collaboration Target a Target that Biogen previously proposed to Sangamo under Section 4.7(b) (Selection of Collaboration Targets) later expires, terminates or is otherwise modified such that such proposed Target would no longer be a Blocked Target, then Sangamo will promptly notify Biogen of such expiration, termination or modification (as applicable).

Blocked Targets. Within [*] days after the receipt of the notice from Novartis nominating a Target as a Replacement Target, Sangamo shall notify Novartis in writing confirming whether: (i) Sangamo has [*] with respect to such Target [*] that is [*] that is [*]; (ii) such Target is [*] that [*]; or (iii) such Target [*] under which [*] (each, a “Blocked Target”). If the Target nominated by Novartis is a Blocked Target, then Novartis may nominate another Target pursuant to Section 4.8(a), which shall be subject to the same confirmation procedure set forth herein. If the Target nominated by Novartis is not a Blocked Target, then such Target shall be a “Proposed Replacement Target” and it shall be submitted by the Parties to the JSC for approval of a Collaboration Plan in accordance with Section 4.2(c).