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Keywords. Key agreement, quantum cryptography, quantum privacy amplification, purification, entanglement, intrinsic mutual information, secret-key rate, information theory.
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Keywords. Author Manuscript
Keywords. Author Manuscript Interrater reliability; pediatric; red flag finding; kappa; emergency medicine; emergency department Headaches are a common chief complaint in children presenting to emergency departments (EDs) in the US, comprising approximately 1% of visits annually.(1–3) Most of these headaches are primary (eg, migraines) or due to conditions such as respiratory infections.(2– 4) However, a small but meaningful proportion (0.5–1%) of headaches are secondary to undiagnosed emergent intracranial abnormalities such as brain tumors, intracranial hemorrhages, or strokes.(2,5–8) Author Manuscript ED clinicians use findings obtained on patient history or physical examination to gauge whether a child with a headache is at high or low risk of having an emergent intracranial abnormality, and to decide whether to obtain emergent neuroimaging.(5,9–14) However, in order for specific clinical findings to guide neuroimaging decision-making appropriately, clinicians must agree on their presence or absence. There are few studies examining interobserver agreement of patient history and physical/neurological examination findings in children with headaches. Clinician agreement is particularly important for children, as patient history and physical examination findings may be more difficult to elicit compared with adults due to differences in developmental capacity, language, and cooperation with the physical examination.(15,16) Findings with adequate agreement can be used across different types of clinicians to guide neuroimaging decision-making and to be considered for incorporation into clinical prediction rules or risk stratification models for identification of children with headaches who are at risk of emergent intracranial abnormalities. These rules or models can help optimize the use of ED neuroimaging, including safely reducing unnecessary sedation and/or exposure to radiation from computed tomography (CT), which is the imaging modality of choice in the ED. Therefore, our objective was to determine the interobserver agreement of patient history and physical examination findings in otherwise healthy children undergoing ED evaluations for headaches.
Keywords. Central bank cooperation; Europe; financial crisis management; logic of appropriateness; macroprudential policy
Keywords. Certain words in this agreement have specific meanings which are explained in clause 21 (Meaning of Words).