RESULTS OF THE SYSTEMATIC REVIEW Sample Clauses

RESULTS OF THE SYSTEMATIC REVIEW. There were a total of 286 citations identified in the initial key word search. Abstract and title review eliminated 267 results. Of the 19 citations left for review, 14 studies were eliminated: eight were based on simulated missing data,21,37–43 three focused on genetic studies,44–46 two did not discuss multiple imputation,47,48 and one lacked comparison with complete-case analysis.49 The remaining five studies24,41–43,49–53 focused on using multiple imputation in actual datasets with missing values that constructed multivariate regression models (Figure 2). A majority of studies included for review were based on retrospective studies;50,52–54 however, there was one based on a prospective study.51 All of the studies used multiple imputation and compared it to complete-case analysis. Two studies included missing indicator methods,51,53 one study examined regression imputation,53 and one study examined conditional/unconditional mean imputation.51 Figure 2. Flow diagram of the literature search. MI, multiple imputation CCA, complete case analysis
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