Cyclophosphamide Sample Clauses

Cyclophosphamide. Cyclophosphamide is a nitrogen mustard-derivative alkylating agent. Following conversion to active metabolites in the liver, cyclophosphamide functions as an alkylating agent; the drug also possesses potent immunosuppressive activity. The serum half-life after IV administration ranges from 3-12 hours; the drug and/or its metabolites can be detected in the serum for up to 72 hours after administration.

Cyclophosphamide. Advice to be given  Empty bladder as completely as possible after urinating  Avoid delay in emptying bladder  Importance of perianal hygiene  Avoid strong coffee and tea  Avoid tight underclothes made of synthetic material  If symptoms are related to sexual intercourse, perianal skin should be washed beforehand; bladder should be emptied before and after intercourse.  If client aged under 25 years old, given information about Chlamydia Screening OTC medication Potassium or sodium citrate containing preparations Cymalon®, For licensed indications, doses, contraindications and other prescribing information – please refer to manufacturers information / SPC – summary product characteristics. Symptoms of pain can be relieved with analgesics such as paracetamol and ibuprofen Non pharmaceutical treatment Drink large quantities of fluids, especially soft drinks e.g. barley water (avoid alcohol / fruit juices) Some evidence that cranberry juice may be of benefit (Not if patient taking warfarin) When to refer  Men  Children  Pregnancy or breastfeeding women  Associated with fever, nausea and / or vomiting  Loin pain or tenderness  Haematuria  Associated with increased thirst / weight loss  No response after 3 days  Diabetics  Vaginal discharge  Recurrent cystitis Definition A change in normal bowel habit resulting in increased frequency of bowel movements and the passage of soft or watery stools Description of symptoms  Rapid onset  Increased frequency of bowel movements and passage of watery/loose stools  Associated with abdominal cramps, flatulence, weakness or malaise Precipitating factors  Ingestion of noxious material, food poisoning  Drugs (e.g. magnesium salts, antibiotics, digoxin (toxicity), colchicines, laxatives)  Viral or bacterial infection Advice to be given  Usually self-limiting condition that only lasts a few days  Rehydration – replacement of lost fluids is usually the only treatment required  Advice regarding sign of dehydration  Advise to drink plenty of clear, non-milky fluids (non- alcoholic). Avoid fizzy drinks  avoid dairy products and cow’s milk  Advice to eat no solid food for 24 hours may be appropriate. For adults, consumption of solid food should be guided by appetite  advise to eat small light meals  avoid spicy or heavy food  advise parent – if condition not settling go and see GP  give patient advice on signs / symptoms of appendicitis Notification If the diarrhoea cause is related to food – NOTIFY th...