Principle Stratification Sample Clauses

Principle Stratification. There are many examples in public health, as well as in other fields, of outcome measures that are referred to as missing, but would be more accurately described as truncated. For example, a clinical trial where the outcome measure can only be assessed on those patients who survive to a given endpoint, or an economic study where salary can only be assessed for those who are employed [Zhang et al., 2006], or an education intervention study, where the effect of the intervention on test scores can only be assessed for those who remain in school [Zhang and Xxxxx, 2003]. All of these examples require a specific type of analysis that accurately takes the truncation of the outcome measure into account.
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Principle Stratification. To conduct the principle stratification analysis described in section 1.4, we would ideally be able to fill out a table such as Table 4.2. Table 4.2: Principle Strata Prob. of Principle Stratum Membership Principle Stratum Si(t) Si(c) Yi(t) Yi(c) πLL πLD πDL πDD LL LD DL DD 1 1 0 0 1 0 1 0 ∈ R ∈* R * ∈* R ∈* R Where Si(Z) is observed mortality status under treatment or control, Yi(Z) is observed outcome (DRS) under treatment and control (which is sometimes a valid DRS score on the real number line and sometimes truncated by death, indicated by *), and LL, LD, DL, and DD refer to the principle strata - those who would live under both treatments, those who would live under control but die under treatment, those who would die under control but live under treatment, and those who would die regardless of treatment, respectively. Instead, what we observe is Table 4.3. Table 4.3: Principle Strata - Observed Observed Group % of population Principle Stratum Zi Si(Z) Y i(Z) (SD) OBS(tL) 55% LL or LD 1 1 1.9 (2.8) OBS (tD) 20% DD or DL 1 0 * OBS (cL) 15% LL or DL 0 1 2.8 (5.3) OBS (cD) 10% DD or LD 0 0 * The principle stratification approach is an attempt to tease out what proportion of the 70% of the sample that consists of a mixture of LL, DL, and LD patients are actually LL, and estimate a treatment effect within this principle strata.

Related to Principle Stratification

  • Construction Change Directive A written order prepared and issued by the District, the Construction Manager, and/or the Architect and signed by the District and the Architect, directing a change in the Work.

  • Construction Change Directives 7.3.1 A Construction Change Directive is written order prepared by the Architect and signed by the Owner and Architect, directing a change in the Work and stating a proposed basis for adjustment, if any, in the Contract Sum, or Contract Time, or both. The Owner may by Construction Change Directive, without invalidating the Contract, order changes in the Work within the general scope of the Contract consisting of additions, deletions or other revisions, the Contract Sum and Contract Time being adjusting accordingly.

  • Principles of cooperation The Parties shall apply the following principles to cooperation activities covered by this Agreement:

  • PRINCIPLES OF COLLABORATION The parties agree to adopt the following principles when carrying out the Project (Principles):

  • DEVELOPMENT OR ASSISTANCE IN DEVELOPMENT OF SPECIFICATIONS REQUIREMENTS/ STATEMENTS OF WORK Firms and/or individuals that assisted in the development or drafting of the specifications, requirements, statements of work, or solicitation documents contained herein are excluded from competing for this solicitation. This shall not be applicable to firms and/or individuals providing responses to a publicly posted Request for Information (RFI) associated with a solicitation.

  • CHANGE DIRECTIVE A Change Directive means a written instruction, which shall be deemed incorporated into and forming part of the Agreement, prepared by the Contract Administrator and signed by the Owner directing the Contractor to proceed with a change in the Work prior to or in the absence of the Owner and the Contractor agreeing upon adjustments in the Contract Price and the Contract Time.

  • Project Implementation 2. The Borrower shall:

  • Implementation Schedule TIME IS OF THE ESSENCE with regard to all dates and time periods set forth and/or incorporated herein. Any material modification or deviation from an approved schedule described in this Agreement shall occur only upon approval of the City and RDA, with any such approvals required to be in writing as an amendment to this Agreement, and which approvals shall not be unreasonably withheld. City shall cooperate and act promptly with respect to any and all permits or approvals necessary for completion of the Project. Notwithstanding the above, this Agreement shall not limit the discretion of the City, or any of its duly appointed and authorized governing bodies, boards or entities, in approving or rejecting any aspect of the Project or improvements contemplated on or about the Property.

  • Protocol No action to coerce or censor or penalize any negotiation participant shall be made or implied by any other member as a result of participation in the negotiation process.

  • STATEMENT OF PHILOSOPHY The University of Minnesota and the Union are committed to recognizing and acknowledging the healthy and positive diversity that we have on the University campuses. Further, the parties recognize that all employees have the right to work in a productive environment in which there is no verbal or physical intimidation, or discrimination or harassment based on the criteria provided in Section 1, Discrimination Prohibition, and Section 2, Sexual Harassment. It is in this spirit that the parties agree to the provisions of this Article. This statement shall not be grievable nor shall either party use this Section as evidence or argument in arbitration.

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