Solubility Differences. This involves extraction and is probably the easiest way, but it is unlikely that one encounters such a simple mixture. One component can be extracted into a solvent, the other component being insoluble. This component can then be isolated by distillation or evaporation of solvent. Normally, solvent with wide differences in polarity are tried first, e.g. water and petroleum ether. Some examples where this method will work are sucrose/ naphthalene, acetamide/ diphenyl and glycine hydrochloride/ benzophenone, where contrasting differences in polarity of the components exist.
