Candidate Gene definition

Candidate Gene has the meaning set forth in Section 4.1(a)(iii).

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Candidate Gene means (a) [**] which has been implicated in a disease or condition in the Field, or (b) [**] in a disease or condition in the Field. The gene must be implicated in the disease or condition in the Field (i) by Millennium prior to the Effective Date or by Millennium, by Lilly or jointly by the parties in the course of the Program and (ii) [**] the Candidate Gene shall mean [**]; or (C) by any other method, including but not limited to expression profiling or other cDNA technique (in which case it shall be appropriately [**] ; all as determined in good faith by the Joint Management Team. Notwithstanding the foregoing, a gene may be designated a Candidate Gene pursuant to Section 5.6. Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions.

Candidate Gene means a Novel Gene which is the subject of a Candidate Gene Identification.

Examples of Candidate Gene in a sentence

• Management Team that the study of such Third Party Gene may lead to further development of such Third Party Gene as a Candidate Gene and Validated Target.

• Upon such notice (and on its own initiative even without notice), the Management Committee shall determine whether a Candidate Gene, Validated Target or Validated Protein has been discovered by the Joint Venture utilizing criteria to be established by the Management Committee and furnished to the parties in writing.

• Upon any such designation(s), each designated Candidate Gene, Candidate Protein Drug and/or Validated Target shall be subject to all terms and conditions of this Agreement that relate to any Candidate Gene, Candidate Protein Drug and/or Validated Target.

• After the term of the Research Program and during the term of the Astra Development Program, Astra shall use [**] to move each Candidate Gene into Validated Target or Validated Protein status.

• Each Niche Product Development Proposal shall include a preliminary development plan to identify and/or develop such a product as well as a description of known linkages between the Specified Indication and any Candidate Gene, Validated Target or Validated Protein.

• If a Candidate Gene does not attain Validated Target or Candidate Protein Drug status within said three (3) year period, then Lilly's exclusive right to use said Candidate Gene in the Field and the area of Oncology shall be converted into a co-exclusive right to use said Candidate Gene in the Field and the area of Oncology, subject to the other terms of this Section 7.

• After the term of the Program and during the term of the Lilly Development Program, Lilly shall commit resources to continue research on Candidate Genes sufficient to move each Candidate Gene into Validated Target or Candidate Protein Drug status within three (3) years from the date of the termination or expiration of the Program.

• The parties agree that during the term of the Program, an isolated gene that has been implicated in a disease or condition in the Field by a third party before or during the term of the Program (a "Third Party Gene") may be designated a Candidate Gene if it is determined by the Joint Confidential Materials omitted and filed separately with the Securities and Exchange Commission.

• The required scope and contents of such disclosure shall be determined by the Management Committee as part of the criteria for determination of discovery of a Candidate Gene, Validated Target or Validated Protein.

• If the CEO believes such a conflict exists during any period in which Executive is receiving severance payments pursuant to this Agreement, the CEO may ask Executive to choose to discontinue the other work or forfeit the remaining severance payments.

More Definitions of Candidate Gene

Candidate Gene means a gene evaluated by Genaissance in the STRENGTH Trial.

Candidate Gene means a Gene whose [*] cDNA sequence is known and whose function has been determined, in whole or in part, in accordance with criteria to be determined by the Management Committee.

Candidate Gene means a gene for which WSU requests Genaissance to provide genotyping services pursuant to the Genotyping Contract.

Candidate Gene means (a) a Genetics Candidate Gene or (b) a Pre-Candidate Gene, or a gene in its pathway, whose function has been [**] before or in the course of the Research Program, as evidenced by at least one IN VITRO model (including appropriate expression in relevant human cells or tissues) and at least one IN VIVO model of disease in which for each model i) the disregulation of the expression of the gene or Protein encoded by the gene, or ii) the modification of the function of the Protein encoded by the gene, results in a statistically significant modified biological response, all as determined in good faith by the Joint Management Team.

Candidate Gene means a Gene whose [*] cDNA sequence is known and whose function has been determined, in whole or in part, in accordance with criteria determined by the Management Committee.

Candidate Gene. A gene that has been implicated in causing or contributing to the development of a particular disease.