Candidate Gene definition

Candidate Gene has the meaning set forth in Section 4.1(a)(iii).
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Candidate Gene means (a) [**] which has been implicated in a disease or condition in the Field, or (b) [**] in a disease or condition in the Field. The gene must be implicated in the disease or condition in the Field (i) by Millennium prior to the Effective Date or by Millennium, by Lilly or jointly by the parties in the course of the Program and (ii) [**] the Candidate Gene shall mean [**]; or (C) by any other method, including but not limited to expression profiling or other cDNA technique (in which case it shall be appropriately [**] ; all as determined in good faith by the Joint Management Team. Notwithstanding the foregoing, a gene may be designated a Candidate Gene pursuant to Section 5.6. Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Asterisks denote omissions.
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Candidate Gene means a Novel Gene which is the subject of a Candidate Gene Identification.
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Examples of Candidate Gene in a sentence

  • Identification of a Candidate Gene Panel for the Early Diagnosis of Prostate Cancer.

  • C., Tavtigian, S.V., de Silva, D., Cuber, A.S., Thomas, Calvez-Kelm, F.L.: A Laboratory Information Management System (LIMS) for a High Throughput Genetic Platform Aimed at Candidate Gene Mutation Screening.

  • Wei Liu, “A Candidate Gene Analysis for Response to Salmonella Enteritidis Challenge or Vaccination in Young Chicks”, 2002, Ph.D. Present Position: Senior Biostatistican, St. Jude’s Childrens Hospital, Memphis,Tennessee.

  • Single-Cell RNA-Seq of Mouse Dopaminergic Neurons Informs Candidate Gene Selection for Sporadic Parkinson Disease.

  • A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium.

  • Bagci, J.T. Epplen, Exome Sequencing Reveals AGBL5 as Novel Candidate Gene and Additional Variants for Retinitis Pigmentosa in Five Turkish Families, Invest Ophthalmol Vis Sci 56(13) (2015) 8045-53.

  • Multiple loci associated with Factor VII levels in European and African Americans from the Candidate Gene Association Resource (CARe) consortium.

  • Re-use and distribution is strictly not permitted, except for Open Access articles.The T2D study samples were genotyped using the Affymetrix Genome-Wide Human SNP Array 6.0. For the ARIC, CARDIA, JHS, and MESA cohorts, genotyping and quality control were completed by the National Heart, Lung, and Blood Institute’s (NHLBI’s) Candidate Gene Association Resource (CARe) at the Broad Institute16.

  • PPARG gene was associated with T2DM by Candidate Gene Association Studies (CGAS) and has been verified in multiple studies (78, 130, 131).

  • The Candidate Gene Association Resource (CARe) project initiated by the National Heart, Lung, and Blood Institute, conducted analyses of genetic variation in cardiovascular, pulmonary, hematological, and sleep-related traits in nine community-based cohorts21.


More Definitions of Candidate Gene

Candidate Gene means a Gene whose [*] cDNA sequence is known and whose function has been determined, in whole or in part, in accordance with criteria to be determined by the Management Committee.
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Candidate Gene. A gene that has been implicated in causing or contributing to the development of a particular disease.
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Candidate Gene means a gene for which WSU requests Genaissance to provide genotyping services pursuant to the Genotyping Contract.
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Candidate Gene means a Gene whose [*] cDNA sequence is known and whose function has been determined, in whole or in part, in accordance with criteria determined by the Management Committee.
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Candidate Gene means a gene evaluated by Genaissance in the STRENGTH Trial.
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Candidate Gene means (a) a Genetics Candidate Gene or (b) a Pre-Candidate Gene, or a gene in its pathway, whose function has been [**] before or in the course of the Research Program, as evidenced by at least one IN VITRO model (including appropriate expression in relevant human cells or tissues) and at least one IN VIVO model of disease in which for each model i) the disregulation of the expression of the gene or Protein encoded by the gene, or ii) the modification of the function of the Protein encoded by the gene, results in a statistically significant modified biological response, all as determined in good faith by the Joint Management Team.
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Related to Candidate Gene

  • Development Candidate means a Compound that meets the Development Candidate Criteria for the initiation of a Development Program for the treatment of CF, and which is the subject of a notice from Vertex to CFFT that Vertex intends to commence formal pre-clinical development of the Compound in the Field pursuant to the provisions of Section 3.1 hereof.

  • Product Candidate means any pharmaceutical product developed, manufactured and/or tested by or on behalf of the Company that has not received a Regulatory Authorization for commercial distribution other than in connection with pre-clinical or clinical trials.

  • Candidate means the person Introduced by the Agency to the Client for an Engagement including any officer, employee or other representative of the Candidate if the Candidate is a corporate body, and members of the Agency’s own staff;

  • Collaboration Compound means any of the following: (a) FG-4592, (b) any HIF Compound (other than FG-4592) that is added to this Agreement pursuant to Section 3.6, and (c) any salts, esters, complexes, chelates, crystalline and amorphous morphic forms, pegylated forms, enantiomers (excluding regioisomers), prodrugs, solvates, metabolites and catabolites of any of the foregoing ((a) or (b)).

  • Collaboration Target means the Initial Collaboration Targets set forth on Exhibit F and any Additional Target or Substitute Target that is selected in accordance with Section 3.3 of this Agreement.

  • Replacement Candidate means any Candidate Introduced by the Agency to the Client to fill the Engagement following the Introduction of another Candidate whose Engagement either did not commence or was terminated during the first 12 weeks of the Engagement;

  • Therapeutic diet means meals served that are soft, low-fat, low-sodium or controlled calorie.

  • Licensed Compounds means: (a) Research Program Active Compounds; (b) Novartis Active Compounds; (c) salts, hydrates, solvates, esters, metabolites, intermediates, stereoisomers and polymorphs of Research Program Active Compounds or Novartis Active Compounds; and (d) prodrugs of Research Program Active Compounds or Novartis Active Compounds (any of the foregoing, a “Licensed Compound”).

  • Commercialization or “Commercialize” means activities directed to marketing, promoting, research and development as required, manufacturing for sale, offering for sale, distributing, importing or selling a product, including sub-licensing or sub-contracting of these activities.

  • Licensed Compound means [***].

  • New Product means the Synology-branded hardware product and Synology-branded accessories contained in the original packaging Customer bought from an authorized Synology distributor or reseller. You may see our “New Product” at Product Support Status.

  • Joint Commercialization Committee or “JCC” has the meaning set forth in Section 3.4 (Joint Commercialization Committee).

  • New Products means any product which is not an Enhanced Product or 2 Existing Product but which is substantially similar to an Existing Product with respect to design and function and possesses reasonable performance improvements. If Company desires to purchase an Enhanced or New Product(s) from Supplier, Company shall so notify Supplier and provide Supplier the opportunity to manufacture such Enhanced or New Product(s), subject to the following conditions and procedures.

  • Alternative nicotine product means any noncombustible product containing nicotine that is intended for human consumption, whether chewed, absorbed, dissolved, or ingested by any other means. "Alternative nicotine product" does not include any nicotine vapor product, tobacco product, or product regulated as a drug or device by the U.S. Food and Drug Administration (FDA) under Chapter V (21

  • Nicotine product means a product that contains nicotine and is not any of the following:

  • Collaboration Product means a pharmaceutical product containing or comprising Compound in any dosage form alone, or in combination with, one or more other pharmaceutically active ingredients, and any and all Improvements thereto.

  • Lead Compound means any compound of lead other than galena which, when treated in the manner described below, yields to an aqueous solution of hydrochloric acid a quantity soluble lead compound exceeding, when calculated as lead monoxide, five percent of the dry weight of the portion taken analysis.

  • Active Pharmaceutical Ingredient or “API” shall mean one or more of the following active pharmaceutical ingredients: tenofovir alafenamide (“TAF”), tenofovir disoproxil fumarate (“TDF”), elvitegravir (“EVG”), and cobicistat (“COBI”).

  • Independent candidate means any candidate who claims not to be affiliated with a political party, and whose name has been certified on the office-type ballot at a general or special election through the filing of a statement of candidacy and nominating petition, as prescribed in section 3513.257 of the Revised Code.

  • Therapeutic Product means a health product categorised as a therapeutic product in the First Schedule to the Act;

  • Antibody means a molecule comprising or containing one or more immunoglobulin variable domains or any fragments, derivatives, variants or modifications thereof that bind to the same antigen.

  • Pharmaceutical Product shall have the meaning ascribed to such term in Section 3.1(hh).

  • Commercialization Plan has the meaning set forth in Section 6.2.

  • Commercialise means to promote, market, distribute, sell and/or otherwise commercialise a product, and Commercialising and Commercialisation shall be construed accordingly;

  • Compounds means any or all of the following chemicals, as the context requires:

  • Vaccine means a specially prepared antigen which, upon administration to a person, will result in immunity and, specifically for the purposes of this rule, shall mean influenza and pneumococcal vaccines.