Dosage and administration definition
Dosage and administration. ADHD3: 25 microgram twice daily gradually increased as required by 25 microgram increments to 75 micrograms twice daily if necessary. Maximum dose 150 micrograms twice daily depending on response and tolerability. Tics3: 25 micrograms to 50micrograms per day, increased in increments of 25 micrograms to 50 micrograms per day every 5 to 7 days. Therapeutic doses are in the order of 3-5 mcg/kg (
Dosage and administration. Adults: All patients receive Azathioprine in a constant dose of 1 - 2 mg/kg/day rounded to the nearest 25 mg. Maintenance dose is then adjusted within these limits to clinical response and tolerance.
Dosage and administration. OCD1: Age 13-17 years: Initially 50 mg once daily. Age 6-12 years: Initially 25 mg once daily. The dosage may be increased to 50 mg once daily after one week. Subsequent doses may be increased in case of less than desired response in 50 mg increments over a period of some weeks, as needed. The maximum dosage is 200 mg daily. The generally lower body weights of children compared to those of adults should be taken into consideration when increasing the dose from 50 mg. Dose changes should not occur at intervals of less than one week. Depression2: Initially 25 mg, gradually increased if clinically necessary to 200 mg over the next 2 to 4 weeks. Lower doses should be considered in children with lower body weight. There is little evidence regarding the effectiveness of the upper daily doses for adults in children and young people, but these may be considered in older children of higher body weight and/or when, in severe illness, an early clinical response is considered a priority. When a child or young person responds to treatment, the sertraline should be continued for at least 6 months after remission (defined as no symptoms and full functioning for at least 8 weeks). Anxiety or PTSD3: Initially 12.5 mg to 25 mg; increase as clinically necessary to within the dose range of 25 mg to 200 mg daily. Administration tips: Many 50 mg tablets are scored; and they can be split on the score line to enable a 25 mg dose4. Wherever possible the child/adolescent should be encouraged to use tablet formulations rather than prescribing a liquid “special” which may cost upwards of £1,000 per year (see cost information below). Crushing the tablets should be avoided as the tablets have a bitter taste and an anaesthetic effect on the tongue5. Enteral tubes: the crushed tablets can be dispersed in water before administering via the tube5. (May take 1 to 5 minutes to disperse). Discontinuation: The dose should be gradually reduced over a period of at least 6 weeks3 to minimise withdrawal effects.
Examples of Dosage and administration in a sentence
Dosage and administration: 60mg every 6 months via subcutaneous injection.
Secondary care - specialist Primary care SUPPORTING INFORMATION Licensed indication Dosage and administration Elderly - Efficacy and safety were comparable in both elderly and younger patients.
Dosage and administration- hypogonadotrophic hypogonadism and testicular failure Low doses are initiated and gradually increased to adult dosage over time, usually started between 12-13 years.
More Definitions of Dosage and administration
Dosage and administration. The daily dosage should begin at 7.2g increasing by 4.8g every three to four days up to a maximum of 24 g, in two or three sub-doses. Treatment with other anti-myoclonic medicinal products should be maintained at the same dosage. Depending on the clinical benefit obtained, the dosage of other such medicinal products should be reduced, if possible. Once started, treatment with piracetam should be continued for as long as the original cerebral disease persists. In patients with an acute episode, spontaneous evolution may occur over time and an attempt should be made every 6 months to decrease or discontinue the medicinal treatment. This should be done by reducing the dose of piracetam by 1.2 g every two days (every three or four days in the case of a ▇▇▇▇▇ and ▇▇▇▇▇ syndrome, in order to prevent the possibility of sudden relapse or withdrawal seizures). Elderly: Adjustment of the dose is recommended in elderly patients with compromised renal function (see 'Monitoring’ below). For long term treatment in the elderly, regular evaluation of the creatinine clearance is required to allow dosage adaptation if needed. Patients with renal impairment: The daily dose must be individualized according to renal function (see monitoring). Patients with hepatic impairment: No dose adjustment is needed in patients with solely hepatic impairment. In patients with hepatic impairment and renal impairment, adjustment of dose is recommended as below.