Slope factor definition

Slope factor. , also known as "q1*", means the incremental rate of cancer development calculated through use of a linearized multistage model or other appropriate model. Slope factor is expressed in milligrams per kilogram per day of exposure to the chemical in question.
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Slope factor means the plausible upper-bound estimate of the probability of a response (cancer) per unit intake of chemical over a lifetime. Also referred to as Potency Factor.
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Slope factor means an upper bound estimate that approximates a 95 percent confidence limit of the increased cancer risk from a lifetime exposure to a contaminant. This estimate is expressed in units of the proportion of a population that is affected per milligram per day exposure to the contaminant per kilogram of body weight of the exposed individual.
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Examples of Slope factor in a sentence

  • Slope factor and carcinogen group of arsenic are those listed in IRIS under arsenic (inorganic); RfDs of chromium, mercury, and nickel are those listed in IRIS under chromium (VI), mercuric chloride, and nickel (soluble salts), respectively.

  • Slope factor is expressed in milligrams per kilogram per day of exposure to the chemical in question.

  • Slope factor setting; (j) Shade factor setting; and (k) Irrigation uniformity or efficiency setting.

  • Where: C = Concentration of contaminant (soil: mg/kg, water: mg/l) RF = Risk factor For protection from cancer health risks:RF = TR ÷ SFWhere: TR = Target cancer risk (unitless)SF = Slope factor [(mg/kg)/day]-1 for a route of exposure; see paragraph “c” for source.

  • It Slope factor is expressed in milligrams per kilogram per day of exposure to the chemical in question.

  • Slope factor: An upper bound, approximating a 95% confidence limit, on the increased cancer risk from a lifetime exposure to an agent.

  • Slope factor (SF) - a plausible upper-bound estimate of the probability of a carcinogenic response per unit intake of a constituent over a lifetime; EPA toxicity value for a constituent that elicits carcinogenic health effects.

  • Secondary Maximum Contaminant Level (SMCL) is given if applicable.B RfD: Chronic oral reference dose for non-carcinogenic toxic health effects based on findings of No Observable Adverse Effect Level (NOAEL) or Lowest Observable Adverse Effect Level (LOAEL).C SF: Slope factor is the upper-bound incremental risk of developing cancer due to lifetime exposure to a particular unit intake.D Chronic refers to the health effects due to long term exposure to the contaminant (e.g., exposure over many years).

  • Slope factor is the cancer risk (proportion affected) per unit of dose.

  • Select Slope to recalculate the Slope factor M (Multiplier) or Offset to recalculate the offset calibration factor A (Adder).


More Definitions of Slope factor

Slope factor means the incremental rate of cancer development calculated using a linearized multistage model or other appropriate model. It is expressed in milligrams per kilogram per day of exposure to the chemical in question and is also known as q1*.
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Slope factor or "Q1*" means the incremental rate of cancer development calculated through use of a linearized multistage model or other appropriate model. It is expressed in (mg/kg/day) of exposure to the chemical in question.
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Slope factor means the upperbound estimate of probability in the occurrence of excess cancer risk (increase in cancer risk over the background risk) associated with a specific carcinogen for an individual who is exposed to a unit of intake over lifetime. The unit for a slope factor is the probability per unit intake, i.e., the inverse of milligram per kilogram body weight (mg/Kg/day)-1.
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Slope factor or "Q *" means the incremental rate of cancer development calculated through use o1 f a linearized multistage model or other appropriate
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Related to Slope factor

  • Load Factor means the percentage of aircraft seats actually occupied on a flight (RPMs divided by ASMs). “NMB” means the National Mediation Board.

  • Class Factor As to any date of determination and any Class of Certificates (other than the Interest Only Classes and the Residual Certificates), a fraction the numerator of which is (i) the aggregate of the denominations of all Certificates of such Class plus, in the case of each Accrual Class, all interest that has accrued on the Certificates of such Class prior to such date of determination and been added to the Class Balance thereof, less (ii) the aggregate amount of all Principal Distribution Amounts, if any, allocable thereto prior to such date of determination and the denominator of which is the original Class Balance of such Class. As to any date of determination and any Interest Only Class, a fraction, the numerator of which is the percentage of the balance specified for such purpose under “Reference Sheet–Notional Classes” in the Prospectus Supplement (or, if applicable, the sum of the applicable percentages of the balances so specified) and the denominator of which is the original Class Balance thereof. Code: The Internal Revenue Code of 1986, as amended, including any successor or amendatory provisions.

  • Leverage Factor means the leverage factor in respect of a Series of ETP Securities as specified in the relevant Final Terms.

  • Fit factor means a quantitative estimate of the fit of a particular respirator to a specific individual, and typically estimates the ratio of the concentration of a substance in ambient air to its concentration inside the respirator when worn.

  • Power Factor means the ratio of usage power measured in kW to total power measured in kVA;

  • Loss Factor means the scaling factor determined in accordance with clause 6 and applied by the reconciliation manager to volumes of electricity measured or estimated in respect of ICPs on the Network, in order to reflect the impact of the ICP on Losses within the Network;

  • Performance Factor means any matter that could or will significantly affect a party’s ability to fulfill its obligations under this Agreement;

  • Adjustment Factor means, with respect to a share of the Fund (or one unit of any other security for which a Fund Closing Price must be determined), 1.0, subject to adjustment in the event of certain events affecting the shares of the Fund. See “—Anti-dilution Adjustments Relating to the Fund; Alternate Calculation —Anti-dilution Adjustments” below.

  • Capacity factor means the ratio of the average load on a machine or equipment for the period of time considered to the capacity rating of the machine or equipment.

  • Performance Factors means any of the factors selected by the Committee and specified in an Award Agreement, from among the following objective measures, either individually, alternatively or in any combination, applied to the Company as a whole or any business unit or Subsidiary, either individually, alternatively, or in any combination, on a GAAP or non-GAAP basis, and measured, to the extent applicable on an absolute basis or relative to a pre-established target, to determine whether the performance goals established by the Committee with respect to applicable Awards have been satisfied:

  • Inflation Factor means a number determined for each tax year by dividing the consumer price index for June of the tax year by the consumer price index for June 2005.

  • Multiplier means the Multiplier specified in the Table.

  • Capacity Utilization Factor or “CUF” shall have the same meaning as provided in CERC (Terms and Conditions for Tariff determination from Renewable Energy Sources) Regulations, 2009 as amended from time to time; However, for avoidance of any doubt, it is clarified that the CUF shall be calculated on the Contracted Capacity; In any Contract Year, if ‘X’ MWh of energy has been metered out at the Delivery Point for ‘Y’ MW Project capacity, CUF= (X MWh/(Y MW*8766)) X100%; Declared CUF for this Project shall be % (to be revised as applicable).

  • Relative TSR means the Company’s TSR relative to the TSR of the companies that comprise the S&P 500 Index as of the last day of the Performance Period, expressed as a percentile.

  • Technique factors means the following conditions of operation:

  • Weighting with respect to an Underlying means the weighting in relation to the relevant Underlying as specified in the table in the definition of such Underlying.