Validated Hit definition

Validated Hit means a Collaboration Hit, Special Collaboration Hit or Non-Field Hit that has met the criteria for validation set forth in the Research Plan. For purposes of this Agreement, (i) the words “include,” “includes” and “including” shall be deemed to be followed by the words “without limitation,” (ii) the word “or” is not exclusive, (iii) the words “herein,” “hereof,” “hereby,” “hereto” and “hereunder” refer to this Agreement as a whole, and (iv) each definition shall be equally applicable to the singular and plural forms of the terms defined. Unless the context otherwise requires, references herein: (A) to Sections and Schedules mean the Sections of and Schedules to this Agreement; (B) to an agreement, instrument or other document means such agreement, instrument or other document as amended, supplemented and modified from time to time to the extent permitted by the provisions thereof and by this Agreement; and (C) to a statute means such statute as amended from time to time and includes any successor legislation thereto and any regulations promulgated thereunder. The Schedules referred to herein shall be construed with and as an integral part of this Agreement to the same extent as if they were set forth verbatim herein.
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Validated Hit means a small molecule that has shown activity against a Target in primary screening as part of the Research Collaboration.
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Validated Hit shall be limited solely to Collaboration Hits identified in a Project Discovery Round that have met the criteria for validation of such type of Collaboration Hit as set forth in the Research Plan.
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Examples of Validated Hit in a sentence

  • Each Special Collaboration Hit that undergoes Core Validation or Model Plant Validation shall constitute a Collaboration Hit hereunder, regardless whether such Special Collaboration Hit qualifies as a Validated Hit.

  • The Research Plan may include a general overview and timetable for development and implementation of the Funded Project, details regarding the Evogene Diligence Obligations and the Monsanto Diligence Obligations, schedules for deliverables, test protocols and procedures, thresholds for determination of a Validated Hit, procedures for disclosing and delivering Collaboration Hits, Special Collaboration Hits, and Preferred Modes of Use to Monsanto, and descriptions of other research activities.

  • Phytera also agrees to deliver all Extracts on a timely basis and to conduct NPCII on Validated Hit Extracts and all other actions required of it in connection with the Program expeditiously and in a scientifically sound manner.

  • Within 30 days of the --------------------------- Committee designation of Validated Hit Extracts, the Parties will proceed to conduct NPCII activities on the Validated Hit Extracts.

  • In the event of Early Termination of this Agreement, pursuant to Section 5.2, the obligations of the Parties to continue to fund NPCII activities that are underway, with respect to specific Validated Hit Extracts at the time notice of Early Termination is received shall survive such termination.

  • Amgen may, in its sole discretion and acting in good faith, designate as a Lead Compound any Validated Hit or any Derivative of a Validated Hit.

  • In the event that Amgen designates as a Lead Compound an Anadys Library Validated Hit that had not been previously deemed an Amgen-Selected Validated Hit, such Anadys Library Validated Hit shall become an Amgen-Selected Validated Hit and shall be subject to Compensation under Section 5(i) of this Agreement.

  • In the event that any Validated Hit selected by Amgen is an Anadys Library Validated Hit, Amgen shall have the option, in its sole discretion, to select such Anadys Library Validated Hit as a Program Compound by providing written notice to Anadys ("Amgen-Selected Validated Hit").

  • If so, the Committee shall then designate between [ ]* Extracts that have been determined to possess Requisite Activity as Validated Hit Extracts.

  • Amgen shall pay Anadys $[...***...] for each such Amgen-SelecTed Validated Hit within thirty (30) days of the foregoing written notice or written notice under Section 3(b) above.


More Definitions of Validated Hit

Validated Hit means a Library Compound or Research Compound that agonizes or antagonizes a Program Target in confirmatory screening of Hits as part of the Research Program.
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Validated Hit means an Anadys Library Validated Hit or an Amgen Library Validated Hit.
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Validated Hit means [***].
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Validated Hit means an Anadys Library Compound or an Aphoenix Library Compound that in a Target Assay yields results that meet the Target Assay Criteria.
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Validated Hit means a Hit that substantially demonstrates:
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Related to Validated Hit

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  • The Project Plan means the document to be developed by the Supplier and approved by the Purchaser, pursuant to GCC Clause 19, based on the requirements of the Contract and the Preliminary Project Plan included in the Supplier’s bid. The “Agreed and Finalized Project Plan” is the version of the Project Plan approved by the Purchaser, in accordance with GCC Clause 19.2. Should the Project Plan conflict with the Contract in any way, the relevant provisions of the Contract, including any amendments, shall prevail.

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  • Project Schedule means a document that, with respect to each Phase of the Project, identifies, coordinates and integrates the anticipated design and construction schedules, the Contracting Authority’s and Owner's responsibilities, government authority reviews and other activities as are necessary for the timely completion of the Work.

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  • Phase II Trial means a clinical trial of a Licensed Product, designated as a Phase II Trial and the principal purpose of which is to make a preliminary determination that such Licensed Product is safe and active in a patient population for its intended use and is designed to obtain sufficient information about such Licensed Product’s efficacy to permit the design of a Phase III Trial(s), and generally consistent with 21 CFR § 312.21(b). For purposes of this definition, Phase II trial shall specifically exclude expansion cohorts from Phase I Trial(s).

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  • Batch means a specific quantity of Product that is intended to have uniform character and quality, within specified limits, and is produced according to a single manufacturing order during the same cycle of manufacture.

  • Phase I Trial means a clinical trial of a Licensed Product in human patients designated as a Phase I Trial and conducted primarily for the purpose of determining the safety of and/or the metabolism and pharmacologic actions of the Licensed Product in humans, as described under 21 CFR § 312.21(a) (as hereafter modified or amended) and any of its foreign equivalents. For purposes of this definition, Phase I Trial shall specifically exclude trials in healthy volunteers.

  • Phase II Study means a study in humans of the safety, dose ranging or efficacy of a product, as further defined in 21 C.F.R. § 312.21(b) (or the equivalent thereof outside the United States).

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