Research Compound definition

Research Compound means a Compound that has not yet been designated a Development Compound.

Research Compound means any DsiRNA-Based Compound that is directed against a Program Target and that is selected for optimization by KHK as an RNA interference therapeutic molecule as part of the Research Collaboration; provided, that, no DsiRNA-Based Compound shall, after becoming a Waived Compound, be designated or nominated as a Research Compound.

Research Compound means: (a) the Initial Research Compound; and (b) a DART (other than the Initial Research Compound, a Compound or a Product) that Binds two (2) targets identified in the Research Agreement against which DARTs will be generated using the DART Platform for evaluation and Development under the Research Agreement.

Examples of Research Compound in a sentence

• The Roche Bioscience Screening Library is not part of the Research Compound Library, but may, in Roche Bioscience's sole discretion, be used in HTS against the Targets.

• Neither Party guarantees the safety or usefulness of any Target, Research Compound or Product.

• KHK shall have the sole right, in its sole discretion, by providing written notice to DICERNA at any time on or before the expiration of the Research Collaboration Term, to (a) designate any DsiRNA-Based Compound as a Research Compound, and (b) determine in its sole discretion not to continue the development and commercialization of any Research Compound against a Program Target.

• During the Term, KHK and its Affiliates will use Commercially Reasonable Efforts to avoid using in any capacity, in connection with the development, manufacture or commercialization of any Research Compound or Licensed Product, any person who, to KHK’s Knowledge has been debarred pursuant to Section 306 (or comparable law or regulation) of the FDCA, or who to KHK’s Knowledge is the subject of a conviction described in such section.

• Neither Party may commence such studies on any Research Compound or Library Compound that is primarily directed against a Target until the Research Management Committee has made such designation.

More Definitions of Research Compound

Research Compound. Research Compound means a Compound containing a Designated Capsid Variant that is the subject of activities under the Research Program.

Research Compound means an Abbott Compound, Icagen Compound, or Overlap Compound that has been selected by the JRC as evidenced by the meeting minutes for additional in vitro and, if justified, in vivo testing, based on having demonstrated in the course of the Research Program a primary mode of action as a modulator of the [**] Target and potency and selectivity for the [**] Target.

Research Compound means a Compound that has not yet met the Success Criteria.

Research Compound means (i) any compound that is designed and screened by XXXXX specifically for PFIZER, and that is delivered to, and selected by, PFIZER pursuant to Section 2.2 of the Screening and Evaluation Agreement and (ii) any salts, esters, ethers, amides, and amines of any compound referred to in clause (i). In connection with clause (ii) of this definition of Research Compound, the parties agree that PFIZER shall be permitted to make any of the changes recited in (ii) to any portion of a Research Compound molecule, including, without limitation, to a base, DNA sugar, backbone moiety, or combinations thereof, provided that [**********************************************] in the [***********************] and [************************* *] of the [***************************] or [*************].

Research Compound means any analog or other derivative compound, including a peptidomimetic, that has been synthesized or acquired pursuant to the Research Plan or at the direction of the Officers as provided in Section 2.5, and is based upon any Validated Hit. [ * ] = Certain confidential information contained in this document, marked by brackets, has been omitted and filed separately with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended.

Research Compound means a compound that is selected by the party which owns or licenses (with a right to sublicense) such compound (or in the case of jointly-owned compounds, selected jointly) and that is evaluated as part of the Research Program.

Research Compound means any MOE Gapmer that modulates the expression of a Selected Gene Target where its primary mechanism of action is through its hybridization to such Selected Gene Target mRNA or pre-mRNA and that is identified by Isis as of the Effective Date or during the Collaboration.