Design Strategy Sample Clauses

Design Strategy. The DF and PS1 scaffolds differ in the inter- helical separation and registry of their four-helix bundle domains (SI Appendix, Fig. S1). Therefore, it was necessary to design linkers that connect the two bundles in an energetically reasonable manner. To accomplish this, the helical bundles were connected using a structure-based design strategy involving two interrelated steps: first, the optimal relative translation and orientation be- tween the bundles, namely the bundle placement, were deter- mined; second, a structural solution interconnecting each of the disjointed helices between the domains was identified. In the most general case, the bundle placement involves searching a six-dimensional space, comprising three translational

Design Strategy. The Dell APEX Service has been designed from the beginning with redundancy and automation at multiple levels to adapt automatically to several different disaster scenarios, such as the sudden unavailability of a data center. The Dell APEX Service also makes use of established hosting providers with sophisticated redundancy to mitigate risks arising from an individual server or disk failure.

Design Strategy. The Moogsoft Service has been designed from the beginning with redundancy and automation at multiple levels to adapt automatically to several different disaster scenarios, such as the sudden unavailability of a data center. The Moogsoft Service also makes use of established hosting providers with sophisticated redundancy to mitigate risks arising from an individual server or disk failure.