Dosage. Child 1 month to 18 years1: The licensed dosing schedule (children of 3 years and over#) for glycopyrronium is based on the weight of the child, starting with approximately 12.8 micrograms/kg per dose three times per day and increasing by the doses listed in the SPC every 7 days. Dose titration should be continued until efficacy is balanced with undesirable effects and amended up or down as appropriate, to a maximum individual dose of 64 micrograms/kg body weight glycopyrronium or 6 ml (1.9 mg glycopyrronium) three times a day, whichever is less. Following the dose titration period, the child's sialorrhoea should be monitored, in conjunction with the carer at no longer than 3 monthly intervals, to assess changes in efficacy and/or tolerability over time, and the dose adjusted accordingly. # Sialanar is not recommended in children below the age of 3 years since there is very limited data on the efficacy and safety of glycopyrronium in this age group Adult population - Sialanar® is indicated for the paediatric population only. There is limited clinical trial evidence on the use of glycopyrronium in the adult population with pathological drooling. Prescribers may consider the unlicensed use of Sialanar for the treatment of hypersalivation in this population following current evidence based guidance3,4 Dosing should be at ≥1 hour before or at least 2 hours after meals or at consistent times with respect to food intake. Avoid high fat food.
Dosage. ● A valid prescription form, written in English that has been approved and countersigned by a suitably qualified and registered healthcare practitioner, who is authorised to prescribe the Products. ● Such other information as the Supplier reasonably requests from time to time.
1. Processing of Personal Data under this agreement shall be limited to such processing activities as the Supplier is reasonably required to undertake in connection with its performance under this agreement.
2. Personal Data will be collected and processed for the following Purpose:
2.1 to allow Patients to receive the Products; and
2.2 to allow the Supplier to provide the Customer with Royal Mail delivery references. This allows the Customer and Patients to track delivery progress via Royal Mail's online delivery tracker website (Internet - xxxxx://xxx0.xxxxxxxxx.xxx/track-your-item#/).
3. The Nature of the processing will be:
3.1 collection, recording and storage;
3.2 structuring and filing including in an organised database;
3.3 access and retrieval; and
3.4 combination with other data.
4. The Duration of the processing under this agreement will be the term of this agreement, and such other period as the Supplier may reasonably require in connection with this agreement, as per clause 24 in IPA embedded in this Schedule 2.
Dosage. The regulated articles must receive the minimum absorbed ionizing radiation dose specified in the PPQ Treatment Manual or in another approved treatment schedule.
Dosage. 1. 1 to a maximum of 4 immunizations; EPI schedule pre- ferred.
Dosage. The dosing of aminophylline varies based on the age and smoking status of the patient. Look it up each time you administer it to ensure proper dosing. Route: Oral or intravenous Nursing Administration Considerations: IV administration should be given over 20 minutes. A smoker is unable to clear aminophylline at the same rate as a non-smoker. It will take the smoker longer to get aminophylline out of the system. Also, patient with heart failure will take longer to clear the medication as well.
Dosage. Children: 1 mcg/kg per dose or 1 mcg/kg/hr as continuous infusion Adult: 50-100 mcg per dose or 1 mcg/kg/hr as continuous infusion Route: IV Nursing Administration Considerations: Give IV dose slowly over 1-2 minutes.
Dosage. Children: 10 mg/kg/dose every 4-6 hours, not to exceed 4 doses daily. Adults: 500-1000 mg per dose every 4-6 hours, not to exceed 4 g per day. Route: IV, oral, and rectal Nursing Administration Considerations: Give slowly over 15 minutes. Side Effects: Jaundice, leukopenia, signs of overdose are signs of liver failure. Drug Interactions: Increased bleeding time for patients on warfarin. (National Health Service, 2007) (Wolters Kluwer Health, 2009)
Dosage. Children: 1 mg/kg Adults: 20-80 mg daily Route: IV and oral Nursing Administration Considerations: Intravenous infusion should be given slowly (over 10- 30 minutes), rapid injection can cause hearing loss and tinnitus. Side Effects: hypokalemia, hyponatremia, mild GI upset, hypotension, hyperglycemia, metabolic alkalosis, vertigo Drug Interactions: Use furosemide with caution in patients also on antihypertensives. Deafness may be worse if furosemide is given with aminogylcosides (Gentamicin).
Dosage. Children: 1 mg/kg in 24 hours given once daily or twice a day. Route: IV or oral Nursing Administration Considerations: Intravenous infusion should be given over 5 minutes. Side Effects: Headache, diarrhea, nausea, vomiting, and dizziness; fever in children (33%) Drug Interactions: Omeprazole increases the effectiveness of warfarin. Uses: Class III antiarrythmic, used to treat ventricular tachycardia and ventricular fibrillation, has also been used to treat supraventricular tachycardia that does not respond to adenosine. Dosage: Children: Load 5 mg/kg over 30 minutes, then follow with a continuous infusion at 5 mcg/kg/min up to 15 mcg/kg/min Route: IV and oral Nursing Administration Considerations: The continuous infusion must be diluted in D5W to a concentration of 2 mg/ml. Side Effects: Hypotension, sinus arrest, cardiac arrhythmias, photosensitivity. Drug Interactions: Increased risk of cardiac toxicity if hypokalemia occurs when given with furosemide. Increased effect of warfarin.
Dosage. The fruits and vegetables must receive a minimum absorbed ion- izing radiation dose of 150 Gray (15 krad).11
