SCREENING OF THE CENTAUR LIBRARY Sample Clauses

SCREENING OF THE CENTAUR LIBRARY. The number of Astra employees participating in each Project in the initial screening of the Centaur Library for Hits will be separately agreed by the parties on a case by case basis but will always include Astra's Project leader and one or more named specialists in chemistry, in modeling and drug design, and in QSAR technologies. The said Astra employees will either alone, or together with the respective Joint Project Teams, be involved in i.a. preparation of proposals to the Steering Committee on Screening Criteria, design of the screens, analyzing results from the screens and identifying Hits from the screens and identifying Lead Compounds. The Astra employees involved in the initial screening of the Centaur Library will be given access to all Structure Information on the Hits but not to Structure Information on other compounds in the Centaur Library except to the extent that is needed or necessary for Identification in a Project as judged by the Joint Project Team and the Steering Committee. Structure Information on compounds disclosed to Astra employees according to the preceding paragraph, and/or on compounds synthesized during the process of Lead Optimization may be disclosed within Astra on a need to know basis. Astra undertakes to keep all Astra employees with access to Structure Information aware of its strictly confidential nature and that the confidentiality obligations undertaken by Astra pursuant to Section 16 of the Agreement applies to such information. Astra further undertakes to identify to Centaur, on a case to case basis, the names of such Astra employees.
Sample 1
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Related to SCREENING OF THE CENTAUR LIBRARY

  • Library Borrowing privileges available without charge. Upon retirement an employee shall be issued a permanent individual library card.

  • Screening After you sign and date the consent document, you will begin screening. The purpose of the screening is to find out if you meet all of the requirements to take part in the study. Procedures that will be completed during the study (including screening) are described below. If you do not meet the requirements, you will not be able to take part in the study. The study investigator or study staff will explain why. As part of screening, you must complete all of the items listed below: • Give your race, age, gender, and ethnicity • Give your medical history o You must review and confirm the information in your medical history questionnaire • Give your drug, alcohol, and tobacco use history • Give your past and current medication and treatment history. This includes any over-the-counter or prescription drugs, such as vitamins, dietary supplements, or herbal supplements, taken in the past 28 days • Height and weight will be measured • Physical exam will be done • Electrocardiogram (ECG) will be collected. An ECG measures the electrical activity of the heart • You may be tested for COVID-19 o Blood tests for human immunodeficiency virus (HIV), hepatitis B, and hepatitis C o Blood tests to see how your blood clots ▪ Fibrinogen ▪ PT/INR/aPTT o Blood tests for amylase and lipase (enzymes that help with digestion, Part B only) o Blood tests for a lipid (fats) panel (Part B only) ▪ Total cholesterol ▪ Triglycerides ▪ HDL ▪ Direct HDL o Blood tests to check your thyroid function (Part B and Part C only) ▪ TSH ▪ Free T4 o Urine to test for drugs of abuse (illegal and prescription) o Urine tests to check your albumin/ creatinine ratio o Females who have not had a period for at least 12 months in a row will have a blood hormone test to confirm they cannot have children • The study investigator may decide to do an alcohol breath test • The use of proper birth control will be reviewed (males only) • You will be asked “How do you feel?” HIV, hepatitis B, and hepatitis C will be tested at screening. If anyone is exposed to your blood during the study, you will have these tests done again. If you have a positive test, you cannot be in or remain in the study. HIV is the virus that causes acquired immunodeficiency syndrome (AIDS). If your HIV test is positive, you will be told about the results. It may take weeks or months after being infected with HIV for the test to be positive. The HIV test is not always right. Having certain infections or positive test results may have to be reported to the State Department of Health. This includes results for HIV, hepatitis, and other infections. If you have any questions about what information is required to be reported, please ask the study investigator or study staff. Although this testing is meant to be private, complete privacy cannot be guaranteed. For example, it is possible for a court of law to get health or study records without your permission.

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