Similar works. The similarity shall be based on the physical size, complexity, methods technology or other characteristics of main items of work viz. earth work, cement concrete, Reinforced cement concrete, brick masonry, stone masonry etc. Average annual construction turnover on the construction works not less than 50% of the probable amount of contract during the last 5 financial years; Note:
i. Annual turnover of construction should be certified by the Chartered Accountant.
ii. Audited balance sheet including all related notes, and income statements for the above financial year to be enclosed.
Similar works. The similarity shall be based on the physical size, complexity, methods technology or other characteristics of main items of work viz. earth work, cement concrete, Reinforced cement concrete, brick masonry, stone masonry etc.
Similar works. The use of a substitution matrix has been proposed before [52, 107]. The former work, [52], presents a dynamic programming theoretical algo- rithm for gapped alignment of two weighted sequences to one another. There is one single score for matches of any kind, one for mismatches of any kind and one for gaps. In that sense, the matrices are in fact not substitution matrices, but rather probability matrices describing the weighted sequences. The score for two aligned positions is the sum of the probabilities of the up to 25 possi- ble combinations (4 bases and 1 gap possibility per position), each factored by one of the three scores (match,mismatch,gap). Sequences with base qualities are converted to weighted sequences by splitting the error probability evenly among to the non–match possibilities (mismatches or gap). The algorithm could easily be converted to use a substitution matrix instead of its base–insensitive scores, but the validity of its scoring formulation has been questioned [107]. Indeed, the is intuitive but arbitrary, without theoretical justification and the simplis- tic weighting mechanism would not handle correctly the weight of scores that reflected sequence similarity. The algorithm also misses the opportunity to by- pass base qualities altogether in order to work directly with the raw sequencing signal, in which case it would have presented an improvement over Slider [21], since the latter deals with raw base signals but does not allow for scores. The work by Xxxxx et al [107], combines a true substitution matrix with quality scores and was tested on 36bp and 51bp–long simulated gap-less reads from the human chromosome 1. The tests carried out are largely similar to the ones carried out in this chapter and both conclude that the use of substitution matrices reflecting sequence evolution is preferable even in the case of short NGS reads. The two works differ in the substitution matrices used, as the work presented here also takes into account the increased mutability of G and C and the base composition bias of the genome, in addition to the transition bias and mutation rate considered by both works. Another difference is the scope of the matrices. The present work focuses on genome resequencing and assumes near identical genome composition between the reference and the sequenced genomes, whereas the work by Xxxxx et al aims at cross–species alignments. Furthermore, the influence of errors that are not reflected by the base qualities is me...
