Visualization. The parties will [*] via [*], [*], [*] and [*]. The [*] CHM [*] and [*] will be [*] and [*] to [*] for usage at [*] as part of the CHM. [*] will [*] the [*] of this [*] on [*] and [*] at [*] on [*] as part of the CHM. OVERALL CHM PROCESS - [*] In addition, an [*] which [*] the [*], [*] and [*] for [*] and [*] the [*] and to [*] of the [*]) will be [*] and [*] to [*] so that [*] can implement necessary [*] within [*] on [*] a part of the CHM. INFORMATION EXCHANGE DURING THE RESEARCH TERM In the course of the [*], a [*] of [*] will need to be [*]. The [*] of the [*], [*], the [*] and of the [*], the [*] and the [*], will be [*] at [*]. [*] will require [*] to the [*]. [*] will be [*] as [*], [*] and [*] for [*] in [*]. The [*] will be * Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions. AZ AND CK CONFIDENTIAL provided for use with [*]. [*] is responsible for acquiring its own [*]. [*] [*] ACCESS TO [*] EMPLOYED DURING THE RESEARCH TERM OF THE COLLABORATION [*] [*] THE CYTOMETRIX(TM) HEPATOTOXICITY MODULE: [*] DELIVERED TO AZ FOR IDENTIFICATION OF HEPATOTOXICITY IN [*] DURING THE [*] [*] of the [*], [*], [*], [*] and [*] for the overall [*] and the [*] will be delivered to [*] during the [*]. [*] will be [*] on the [*] and [*] of the CHM per the [*]. [*] and [*] with [*] for [*], [*] and [*] will be delivered. The [*] will constitute the [*] of the Cytometrix(TM) Hepatotoxicity Module, from [*] to [*] of a [*]. [*] on the [*] and [*] will be provided. [*] [*] [*] [*] [*] * Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions. AZ AND CK CONFIDENTIAL [*] THIRD PARTY PRODUCTS INCLUDED IN THE DELIVERABLES [*] INFORMATION EXCHANGE [*] [*] [*] [*] ALGORITHMS USED AS PART OF THE RESEARCH PLAN [*] [*] [*] [*] CYTOMETRIX(TM) HEPATOTOXICITY MODULE Hardware systems: All computers are to be Intel(R) Pentium(R) series, operating systems are to be Microsoft(R) Windows(R) 2000 or above. (Memory, processor requirements TBD) Applications Software: [*] [*] [*] [*] [*] * Certain information on this page has been omitted and filed separately with the Commission. Confidential treatment has been requested with respect to the omitted portions. AZ AND CK CONFIDENTIAL [*] [*] [*] [*] * Certain information on this page has been omitted and filed sepa...
Visualization. Any technique for creating images, diagrams, or animations to communicate information. BIM can be used as a tool to show visual clarity of simple and complex systems and data to help understand project scope, design options, constructability, coordination and for QA/ QC.
Visualization. In the TC model, a process is given from (a family of) transitions and an asso- ciative array. In the following, we introduce modalities to represent and combine these components graphically. Associative arrays are represented as a list of associations, rendered in a box: k0 : A(k0) k1 : A(k1)
Visualization. 1. After the gel has been dried, open the chamber lid and carefully remove the gel from the electrophoresis chamber.
2. Remove the Gel Holder from the stainer chamber. Attach the gel to the holder by placing the round hole over the left pin and the obround hole over the right pin.
3. Place the Gel Holder with the attached gel facing backwards into the stainer chamber.
4. Use the arrows under STAINER UNIT to select the appropriate test. Press START and choose an operation to proceed. The instrument will stain, destain and dry the gel.
5. When the process is completed, the instrument will beep. Remove the Gel Holder from the stainer and scan the bands in a densitometer.
Visualization. The standard construction of our distance matrix enabled our tool to employ existing techniques to create a two-dimensional image. The intermediate Euclidean distances in this image correspond as good as possible to the distances in the original matrix. Earlier research [11] showed that automated clustering methods with human intervention might get promising results. The method that we incorporated in our tool was described in Chapter 4 and [5], where we built upon the push-and-pull architecture described in [20], and allows data analysts to correct small mistakes made by naive clustering algorithms that result in local optima. The user is assisted by coloring of the nodes that represent how much a single individual or a collection of individuals contribute to the total error made in the current clustering. The end result is a clickable two-dimensional image of all possible careers. When the user clicks on an individual he or she is presented with the profile information for that particular offender. A standard K-means algorithm was used to automatically find clusters in the visual- ization. These clusters correspond to the large groups in the visualization and can be seen as an internal model of the visualization. If such a cluster is viewed as a representation of a certain class of criminal careers the internal clustering can be used to classify new individuals in the visualization by finding out in which cluster they reside. Note that an incremental visualization method is needed to correctly add such a new individual in the first place.
Visualization. 1. After the gel has been dried, carefully remove the gel from the electrophoresis chamber.
2. Remove the Gel Holder from the stainer chamber. Attach the gel to the holder by placing the round hole in the gel backing over the left pin on the holder and the obround hole over the right pin on the holder.
Visualization. 1. After electrophoresis is complete, open the chamber lid and use the Gel Block Remover to remove both gel blocks from the gel. Lift the Gel Holder from the stainer chamber. Attach the gel to the holder by placing the round hole in the gel mylar over the left pin on the holder and the obround hole over the right pin on the holder.
2. Place the Gel Holder with the attached gel facing backwards into the stainer chamber.
3. With ALKALINE HEMOGLOBIN on the display, press the START/STOP button. An option to either begin the test or skip the operation will be presented. Press START/STOP again to begin. The instrument will stain, destain and dry the gel.
4. When the process is complete, the instrument will beep. Remove the Gel Holder from the stainer. Take the gel off of the holder and replace the holder.
Visualization. 1. After electrophoresis is complete, open the chamber lid and use the Gel Block Remover to remove the gel blocks. Replace the electrodes on each end of the gel to prevent curling during drying.
2. Close the chamber lid and press the TEST SELECT/CONTINUE button to dry the gel.
3. After the gel has been dried, carefully remove the gel from the electrophoresis chamber.
4. Remove the Gel Holder from the stainer chamber. Attach the gel to the holder by placing the round hole in the gel backing over the left pin on the holder and the obround hole over the right pin on the holder.
5. Place the Gel Holder with the attached gel facing backwards into the stainer chamber.
6. With the appropriate test name on the display, press the START/STOP button. An option to either begin the test or skip the operation will be presented. Press START/STOP to begin. The instrument will stain, destain, and dry the gel.
7. When the process is completed, the instrument will beep. Remove the Gel Holder from the stainer and scan the bands in a densitometer. Qualitative evaluation: The urine and CSF samples run on the SPIFE Split Beta SPE Gel can only be qualitatively inspected for the presence of the bands. Quantitative evaluation: Scan the serum samples on the SPIFE Split Beta SPE Gel at 595 nm, agarose side down, on an EDC densitometer. Scan the gel agarose side up, on other instruments. A slit size of 5 is recommended. If a QuickScan 2000 is used, scan on the acid blue setting. Stability of End Product: The completed, dried SPIFE Split Beta SPE Gel is stable for an indefinite period of time. Quality Control: SPE Normal (Cat. No. 3424) and SPE Abnormal (Cat. No. 3425) may be used to verify all phases of the procedure and should be used on each gel run. If desired, a control or patient sample may be diluted 1:7 with 0.85% saline (1 part sample + 6 parts saline) and run with urines and CSFs for qualitative comparison. Refer to the package insert provided with the control for assay values.
Visualization. 1. After the gel has been dried, open the chamber lid and carefully remove the gel from the electrophoresis chamber.
2. Remove the Gel Holder from the stainer unit. Attach the gel to the holder by placing the round hole in the gel backing over the left pin on the holder and the obround hole over the right pin on the holder.
3. Place the Gel Holder with the attached gel facing backwards into the stainer unit.
4. With the appropriate test name on the display, press the START/STOP button. An option to either begin the test or skip the operation will be presented. Press START/STOP to begin. The instrument will stain, destain and dry the gel.
5. When the gel has completed the process, the instrument will beep. Remove the Gel Holder from the stainer.
Visualization. 1. After electrophoresis is complete, open the chamber lid and use the Gel Block Remover to remove the gel blocks. Dispose of blades and cups as biohazardous waste. Place one electrode across each end of the gel to prevent curling during drying.
2. Close the chamber lid, and press the TEST SELECT/CONTINUE button to dry the gel.
3. After the gel has been dried, open the chamber lid and carefully remove the gel from the electrophoresis chamber.
4. Remove the Gel Holder from the stainer unit. Attach the gel to the holder by placing the round hole in the gel backing over the left pin on the holder and the obround hole over the right pin on the holder.
5. Place the Gel Holder with the attached gel facing backwards into the stainer unit.
6. With HIGH RESOLUTION on the display, press the START/STOP button. An option to either begin the test or skip the operation will be presented. Press START/STOP to begin. The instrument will stain, destain, and dry the gel.
7. When the gel has completed the process, the instrument will beep. Remove the Gel Holder from the stainer.
