Hit Compound definition

Hit Compound means a Pre-Hit Compound that meets the criteria set forth in the Research Plan.

Hit Compound means any chemical entity that meets the Hit Compound Criteria.

Hit Compound means a Library Compound that in a Target Assay yields results that meet the Target Assay Criteria, but excluding any Library Compound that Gilead can document as previously having been shown to have potential activity against Target. ***CONFIDENTIAL TREATMENT REQUESTED

Examples of Hit Compound in a sentence

• The earlier of (i) designation of the first Hit Compound (as defined under the OCA) for such Collaboration Target by the JRC (as defined under the OCA), or (ii) identification of the first Collaboration Compound to meet Hit Compound Criteria for such Collaboration Target.* $500,000 2.

• Disputes among the JRC or the Parties as to whether to change or add to the Hit Compound Criteria and/or the Lead Compound Criteria shall be non-justiciable, and the Hit Compound Criteria and the Lead Compound Criteria shall remain as they exist as of the Effective Date unless the Parties otherwise agree in writing.

• InterMune shall pay to Array the following amounts [ * ] following the first achievement by Array or by InterMune or its Affiliates, Sublicensees or other designees, as the case may be, of each of the following milestones with respect any [ * ] or Product that itself, or the manufacture, use or sale of which is claimed by a Valid Claim or that incorporates as its active ingredient a Hit Compound that was identified as such pursuant to the Research Collaboration (a “Milestone Product”).

• Array will keep InterMune reasonably informed of the preparation filing, prosecution and maintenance of the other Preparatory Patents to the extent relevant to any Hit Compound, Lead Compound or Product.

• The Research Plan may be amended by the JRC, during the Research Term, based upon the results achieved in the Research Program, provided that the FTE commitments set forth in Section 3.4, together with the definitions of Pre-Hit Compound, Hit Compound and Lead Compound, remain unchanged and such amendment does not violate or contradict any provision of this Agreement.

More Definitions of Hit Compound

Hit Compound means any Collaboration Compound that meets the Hit Compound Criteria with respect to a Collaboration Target.

Hit Compound means a Collaboration Compound that demonstrates any reproducible, significant activity in an assay that searches for activity that may be useful in the Field. The JRC will establish the level of activity and specificity required to constitute a "Hit Compound."

Hit Compound means a compound that has an [********] in a Corrector biological assay, as defined in section 13 below.

Hit Compound means a Novartis Compound for which Avalon, in the course of the Project, finds activity modulating the Pathway at/or below the concentration threshold defined in advance of the start of the Project by the Parties.

Hit Compound means any chemical entity that is determined in performing the Research Plan to meet the Hit Criteria.

Hit Compound means any Activator Compound that is demonstrated by initial screening (x) in the Research Program or (y) by Curis (with respect to Compounds Controlled by Curis) prior to the Effective Date, to have Pathway Activator Activity at a minimum level specified by the JSC.

Hit Compound means any Compound demonstrating activity in an assay conducted by or on behalf of CombinatoRx pursuant to the Research Plan where (i) such Compound has not prior to such time been identified as a CombinatoRx Compound, and (ii) such activity meets any applicable minimum threshold set therefor by Angiotech in the Research Plan, all of which Compounds shall be presented to Angiotech along with all available data promptly after identification, as well as all Compounds included in the Compound Class determined for such Compound pursuant to Section 4.1.2.