Hit Compound definition

Hit Compound means any chemical entity that meets the Hit Compound Criteria.

Hit Compound means a Pre-Hit Compound that meets the criteria set forth in the Research Plan.

Hit Compound means a Library Compound that in a Target Assay yields results that meet the Target Assay Criteria, but excluding any Library Compound that Gilead can document as previously having been shown to have potential activity against Target. ***CONFIDENTIAL TREATMENT REQUESTED

Examples of Hit Compound in a sentence

• From time to time, either Party may suggest that the JRC consider a particular Hit Compound or Lead Compound to be recommended to IIII for selection for further development.

• For each Hit Compound, Lead Compound and Product, as between the Parties, IIII shall be responsible, at its sole expense, for conducting all clinical development of such Lead Compound or Product following the termination of the Research Term, and all commercialization of such Hit Compound, Lead Compound or Product.

• Disputes among the JRC or the Parties as to whether to change or add to the Hit Compound Criteria and/or the Lead Compound Criteria shall be non-justiciable, and the Hit Compound Criteria and the Lead Compound Criteria shall remain as they exist as of the Effective Date unless the Parties otherwise agree in writing.

• IIII shall have the right, [ * ], to (i) prepare, file, prosecute and maintain Collaboration Patents directed to Hit Compounds, Lead Compounds and/or Products; pharmaceutical compositions containing a Hit Compound, Lead Compound, and/or a Product; and methods of making or using any of the foregoing; and (ii) conduct any interferences, re-examinations, reissues and oppositions relating thereto.

• AAAA will keep IIII reasonably informed of the preparation filing, prosecution and maintenance of the other Preparatory Patents to the extent relevant to any Hit Compound, Lead Compound or Product.

More Definitions of Hit Compound

Hit Compound means a Collaboration Compound that demonstrates any reproducible, significant activity in an assay that searches for activity that may be useful in the Field. The JRC will establish the level of activity and specificity required to constitute a "Hit Compound."

Hit Compound means any Collaboration Compound that meets the Hit Compound Criteria with respect to a Collaboration Target.

Hit Compound means any Compound demonstrating activity in an assay conducted by or on behalf of CombinatoRx pursuant to the Research Plan where (i) such Compound has not prior to such time been identified as a CombinatoRx Compound, and (ii) such activity meets any applicable minimum threshold set therefor by Angiotech in the Research Plan, all of which Compounds shall be presented to Angiotech along with all available data promptly after identification, as well as all Compounds included in the Compound Class determined for such Compound pursuant to Section 4.1.2.

Hit Compound means any chemical entity that is determined in performing the Research Plan to meet the Hit Criteria.

Hit Compound means a compound that has an [********] in a Corrector biological assay, as defined in section 13 below.

Hit Compound means a Novartis Compound for which Avalon, in the course of the Project, finds activity modulating the Pathway at/or below the concentration threshold defined in advance of the start of the Project by the Parties.

Hit Compound means any Activator Compound that is demonstrated by initial screening (x) in the Research Program or (y) by Curis (with respect to Compounds Controlled by Curis) prior to the Effective Date, to have Pathway Activator Activity at a minimum level specified by the JSC.