PD-1 Antagonist definition

PD-1 Antagonist means any small or large molecule that blocks binding of PD-L1 and/or PD-L2 to PD-1.

PD-1 Antagonist means any small or large molecule that [*].

PD-1 Antagonist means any [***].

Examples of PD-1 Antagonist in a sentence

• During the Term and continuing [***], Corvus agrees to negotiate exclusively with Genentech for a period of [***] prior to entering into any clinical study or clinical development agreement with a Third Party involving the combination of Corvus Molecule and any PD-L1 Antagonist or PD-1 Antagonist.

• Notwithstanding the foregoing, and notwithstanding any implication to the contrary in this Agreement, Collaborator shall have no right to include any PD-1 Antagonist other than the MSD Compound in the Collaborator Clinical Trial.

• Notwithstanding such Freedom-to-Operate License, in no event shall: (i) MSD have the right to exploit such licensed Patents to sell any Collaborator Class Compound, either alone or as part of a combination (including the Combination); or (ii) Collaborator have the right to exploit such licensed Patents to sell any PD-1 Antagonist, either alone or as part of a combination (including the Combination).

• For the avoidance of doubt, any Invention generically encompassing the Merck Compound or another PD-1 Antagonist (and not the Antigen Express Compound) within its scope, even where the Merck Compound or other PD-1 Antagonist is not disclosed per se, is a Merck Invention.

• Merck hereby grants to Company a non-exclusive, worldwide, royalty-free, fully paid-up, transferable and sublicensable license to any patent Controlled by Merck that [*****] (the “Merck Background Patents”) solely for [*****]; provided, however, that in no event shall Company have the right to use Merck Background Patents to commercialize the Merck Compound or any PD-1 Antagonist.

More Definitions of PD-1 Antagonist

PD-1 Antagonist means any molecule that selectively binds to and interferes with or otherwise blocks signaling of the programmed cell death 1 receptor (PD-1) pathway, other than the Regeneron Product.

PD-1 Antagonist means any molecule that [***].

PD-1 Antagonist means [***].

PD-1 Antagonist means any small or large molecule that [***].

PD-1 Antagonist means [***]. 1.62. “Person” means any individual, sole proprietorship, partnership, corporation, business trust, joint stock company, trust, unincorporated organization, association, limited liability company, institution, public benefit corporation, joint venture, entity or governmental entity. 1.63. “Pharmacovigilance Agreement” has the meaning set forth in Section 5.1. 1.64. “Premarket Approval” is the FDA process of scientific and regulatory review to evaluate the safety and effectiveness of Class III medical devices. Class III devices are those that support or sustain human life, or those that present a potentially high risk for a patient, are of substantial importance in preventing impairment of human health, or which present a potential, unreasonable risk of illness or injury. Heart valves, cochleary implants, and defibrillators are examples of Class III medical devices. 1.65. “Project Manager” has the meaning set forth in Section 3.10.1. 1.66. “Protocol” means the written documentation that describes the Study and sets forth specific activities to be performed as part of the conduct of the Study. 1.67. “Receiving Party” has the meaning set forth in the definition of Confidential Information. 1.68. “Regulatory Agreement” means that certain regulatory agreement regarding the Combination to be entered into by the Parties pursuant to Section 3.9, as the same may be amended from time to time. 1.69. “Regulatory Approvals” means, with respect to the MSD Compound, the Novocure Device, or the Combination (in each instance as the context may require), any and all

PD-1 Antagonist means any ***. *** Portions of this page have been omitted pursuant to a request for Confidential Treatment filled separately with the Commission.

PD-1 Antagonist means any […***…] inhibit the receptor known as Programmed Cell Death protein 1 (“PD-1”) and “PD-L1 Antagonist” means any […***…] inhibit the ligand known as Programmed Cell Death ligand 1 (“PD-L1”). For clarity, “Competing Product” shall not include […***…].