Examples of Special populations in a sentence
Special populations Renal and hepatic impairmentNo dose adjustment is required.
Special populations ElderlyNo dose adjustment is recommended based on age.
Special populations Renal impairment Upadacitinib AUC was 18%, 33%, and 44% higher in subjects with mild (estimated glomerular filtration rate 60 to 89 mL/min/1.73 m2), moderate (estimated glomerular filtration rate 30 to59 mL/min/1.73 m2), and severe (estimated glomerular filtration rate 15 to 29 mL/min/1.73 m2) renal impairment, respectively, compared to subjects with normal renal function.
Special populations ElderlyNo pharmacokinetic data in elderly patients are available.
Special populations Elderly (over 65 years of age)No dose adjustment is needed in the elderly population provided that the renal function is not disturbed.