Retrospective Medical Datasets and Open Data Examination Sample Clauses

Retrospective Medical Datasets and Open Data Examination. For breast cancer, five retrospective datasets from three partners are available to be used in the ASCAPE. Barcelona pilot has a dataset of n = 203 early breast cancer patients treated with different treatment approaches and includes detailed information about patient- and tumour characteristics, treatment strategies, side effects, and QoL aspects gathered through validated questionnaires as EQ-5D. Of the 203 patients of the cohort, retrospective data will only be given from those patients that will not participate in the prospective pilot, therefore avoiding using retrospective and prospective data from the same participants. CareAcross brings a dataset of n = 1,700 breast cancer patients with early or metastatic breast cancer treated with different treatment approaches. The dataset includes data about tumour characteristics, treatment strategies, and side effects based on patients’ answers through an online platform. Örebro pilot brings three retrospective breast cancer datasets. The Sörmland dataset is a research database including n = 232 early breast cancer patients treated with endocrine therapy after surgery. The aim of the Sörmland study was to investigate the incidence of joint pain due to endocrine therapy and its impact on several QoL issues as fatigue, insomnia, anxiety, and depression. Validated questionnaires (Brief Pain Inventory and Fibromyalgia Impact Questionnaire) were used for this purpose. The Uppsala dataset is a dataset aimed to investigate the impact of different surgical approaches on QoL. The dataset included n = 250 early breast patients who fulfilled validated questionnaires (Breast-Q and DASH) before and after surgery. Data on patient- and tumour characteristics as well as treatment strategies were also gathered. Finally, the BcBaSe is a research dataset based on national epidemiological databases in Sweden with data about patients with early breast cancer (n = 15,000) in terms of patient- and tumour characteristics, treatment strategies, prescribed medications, newly diagnosed diseases after breast cancer diagnosis, number and reasons of hospitalizations. This dataset does not include QoL issues captured through questionnaires but it is able to use proxy for some QoL issues of interest as anxiety, depression, insomnia, neurotoxicity where the prescription of a new medication with one of the above mentioned indications can be considered as a proxy for the presence of the specific condition.
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