Day 1 definition
Examples of Day 1 in a sentence
The eGFR based on CKD-EPI equation will be repeated at Check-in (Day -1) to confirm renal impairment status.
On the morning of Day 1, after at least an 8-hour fast, a single oral dose of 200 mg LOXO-305 will be administered with approximately 240 mL of water.
Subjects will be in good general health, except for additional specific inclusion criteria related to subjects with renal impairment, based on medical history, physical examination findings, vital sign measurements, 12-lead ECG, and clinical laboratory evaluations at Screening and/or Check-in (Day -1), as determined by the Investigator (or designee).
Subjects will be confined at the CRU from the time of Check-in (Day -1) until End of Treatment (EOT) on Day 8 upon completion of all PK and safety assessments or Early Termination (ET) if the subject discontinues.
Subjects will be confined at the CRU from the time of Check-in (Day -1) until EOT on Day 8 upon completion of all PK and safety assessments or Early Termination (ET) if the subject discontinues.