Discovery Plan. The Discovery Plan for the [*] Discovery Program shall be added to the Supplemental Information Package as Exhibit A-4, thereto.
Discovery Plan. The Discovery Program shall be carried out in accordance with a mutually agreed upon written Discovery Plan, which shall establish specific research objectives and the research tasks to be performed and resources to be provided by each Party. The initial Discovery Plan establishes: (i) the scope of the research activities which will be performed; (ii) the research objectives and work plan activities with respect to the Discovery Program; (iii) specific screening assays for identifying and testing the activity of Compounds and Library Compounds against the Targets and Trk; (iv) the criteria for determining when a Compound shall be deemed an Active Compound; and (v) the criteria for determining when an Active Compound shall be deemed a Clinical Candidate. The Discovery Plan shall be reviewed on an ongoing basis and may be amended by the Joint Research Committee in accordance with Article 3.
Discovery Plan. Within thirty (30) days following the Effective Date, Agios shall prepare and deliver to Celgene and, within fifteen (15) days after the establishment of the JRC, the JRC shall approve, a Discovery Plan (the “Discovery Plan”) which shall set forth the prioritization of Collaboration Targets, initial validation work to be conducted with respect to Collaboration Targets, anticipated post-validation discovery research activities to be conducted under a Discovery Program, and the Party responsible for performance of an activity (which shall be Agios unless both Agios and Celgene otherwise agree). Thereafter, the JRC shall approve updates to the Discovery Plan on a quarterly basis during the Option Term (or, if applicable, with respect to any Extended Program, during any Post-Option Extension).
Discovery Plan. 3.3.1. The Discovery Program shall be carried out in accordance with a mutually agreed upon written Discovery Plan. The Discovery Plan shall establish specific research objectives and the research tasks to be performed and resources to be provided by each Party. The initial Discovery Plan establishes:
(a) the scope of the research activities which will be performed;
(b) the research objectives and work plan activities with respect to the Discovery Program;
(c) specific screening assays for identifying and testing the activity of Compounds and Library Compounds against the Targets;
(d) the criteria for determination of a Drug Candidate. The initial Discovery Plan approved by the JSC in accordance with Article 6 shall be the operative Discovery Plan, which shall be reviewed on an ongoing basis and may be amended by the JSC in accordance with Article 6.
3.3.2. The JRC shall prepare a detailed Discovery Plan and thereafter on a regular basis (at least annually), propose updates to the Discovery Plan which shall include without limitation, any required or appropriate amendments, changes, and additions to the Discovery Plan, a specification of each Party’s specific research activities, the allocation of responsibilities with respect thereto, and the Discovery Plan Budget and the timelines associated with the research activities to be carried out by each Party under the Discover Program. Any such proposed updated Discovery Plan shall be submitted to the JSC for its prior review and approval. Upon approval by the JSC, the Discovery Plan shall forthwith govern the Discovery Program with respect to the Targets. Any dispute between the Parties in the JSC regarding any updated Discovery Plan shall be resolved in accordance with Section 6.4 (Disputes).
Discovery Plan. Upon exercise of the Option, the JAC or its designated subcommittee will provide recommendations to the Parties for any modifications to the Discovery Program, including without limitation any proposed modifications to the Clinical Candidate Criteria (with corresponding proposed updates to Schedule 4.1.2, as applicable). At such time, the Parties will agree upon a budget setting forth the amounts to be paid to Array during its performance of the Discovery Program, and subject to and in accordance with Article VII.
Discovery Plan. The Discovery Program shall be carried out in accordance with a mutually agreed upon written discovery plan, which shall establish specific research objectives and the research tasks to be performed and resources to be provided by each Party (herein, the “Discovery Plan”). Within [***] of Mirati’s exercise of the Option, the Parties shall develop and finalize the Discovery Plan. The Discovery Plan also will include [***]. The Discovery Plan shall be reviewed on an ongoing basis and may be amended only by written agreement of the Parties.
Discovery Plan. If the monitors encounter human remains, including cremated human remains, during monitoring or any construction activities, they shall be treated in accordance with Stipulation VI, Treatment of Human Remains, and Appendix F, Human Remains Protocol.
Discovery Plan. The Discovery Plan under a Discovery/Development Program shall set forth, at a minimum: (i) Candidate Product Criteria with respect to the applicable Target; (ii) the specific activities to be conducted by ZEALAND in order to identify Candidate Products from any previously identified, existing or new molecules meeting the Candidate Product Criteria and provide ALEXION with sufficient data and information with respect to such Candidate Product(s) for ALEXION to determine whether to designate such Candidate Product as an Existing Lead Product, Created Lead Product, or Optioned Product, as applicable; and (iii) a proposed timeline and budget for the performance of the Discovery Plan (“Discovery Plan”).
Discovery Plan. During each Discovery Plan Term, ZEALAND will deliver to ALEXION samples of all peptide(s) or other molecule(s) that meet the Candidate Product Criteria set forth in the applicable Discovery Plan, together with a report as set forth in Section 2.4, summarizing the Results and Deliverables of the Discovery Plan within [***] days of submission to ALEXION of each such peptide(s) or other molecule(s). With respect to peptides or other molecules evaluated by ZEALAND which did not meet the Candidate Product Criteria but [***], the Results and Deliverables shall also include the identities of such other peptides or molecules and the results of each such evaluation. ZEALAND shall deliver to ALEXION, upon its written request, samples of each peptide or other molecule that did not meet the Candidate Product Criteria but [***] and sufficient data and information with respect to such peptide or molecule for ALEXION to determine whether to designate such peptide or molecule as an Existing Lead Product, Created Lead Product, or Optioned Product as applicable. Any and all costs incurred by ALEXION in the evaluation of such Candidate Products or such other molecules by ALEXION during the applicable Evaluation Period shall be borne by ALEXION.
Discovery Plan
