ACTIVE HOMOLOG definition

ACTIVE HOMOLOG means any ArQule Derivative Compound or Monsanto Derivative Compound that exhibits substantial homology with an Active ArQule Compound or Active Monsanto Compound, respectively, as determined by the Research Committee.
ACTIVE HOMOLOG means (i) any ArQule Compound that exhibits substantial homology with an Active Compound in the same Mapping Array or (ii) any Directed Array Compound that exhibits substantial homology with an Active Compound in the same Directed Array Program, with "substantial homology" determined by Monsanto in good faith according to predetermined thresholds set by Monsanto in good faith.
ACTIVE HOMOLOG means any ArQule Compound within the same Chemical Theme as an Active ArQule Compound that exhibits substantial structural homology with such Active ArQule Compound and exhibits minimal functional activity. The criteria for determining "substantial structural homology" and "minimal functional activity" for each Active ArQule Compound are established by the Research Committee acting in accordance with Section 2.

More Definitions of ACTIVE HOMOLOG

ACTIVE HOMOLOG means any ArQule Derivative Compound or Sankyo Derivative Compound that exhibits substantial homology with an Active Compound as determined by the Steering Committee.
ACTIVE HOMOLOG means any ArQule Compound within the same Chemical Theme as an Active ArQule Compound that exhibits substantial structural homology with such Active ArQule Compound and exhibits minimal functional activity. The criteria for determining “substantial structural homology” and “minimal functional activity” for each Active ArQule Compound are established by the Research Committee acting in accordance with Section 2.
ACTIVE HOMOLOG means any Sugen Derivative Compound that exhibits Substantial Homology with an Active Sugen Compound as determined by Sugen using appropriate business and scientific criteria.
ACTIVE HOMOLOG. 1.2. "Active ArQule Compound" 1.3. "Active Compound" 1.4. "Active Sankyo Compound" 1.5. "Affiliate" 1.6. "Agreement" 1.7. "ArQule Compound" 1.8. "ArQule Derivative Compound" 1.9. "ArQule Patent Rights" 1,10. "ArQule Technology" 1.11. "Array" 1.12. "Base Rate of Interest" 1.13. "Chemical Theme" 1.14. "Confidential Information" 1.15. "Contract Year" 1.16. "Derivative Compound" 1.17. "Directed Array (tm)" 1.18. "Directed Array (tm) Program" 1.19. "Disclosing Party" 1.20. "Effective Date" 1.21. "Extraordinary Expenses" 1.22. "FDA" 1.23. "Joint Patent Rights" 1.24. "Licensed Compound" 1.25. "Licensed Compound Set" 1.26. "Mapping Array (tm)" 1.27. "Mapping Array (tm) Program" 1.28. "Net Sales" 1.29. "Net Sales Price" 1.30. "Party" 1.31. "Patent Rights" 1.32. "Phase I Clinical Trials" 1.33. "Phase II Clinical Trials" 1.34. "Phase III Clinical Trials" 1.35. "Preclinical Compound" 1.36. "Preclinical Development" 1.37. "Receiving Party" 1.38. "Research Period" 1.39. "Research Program" 1.40. "Research Plan" 1.41. "Royalty-Bearing Product" 1.42. "Royalty Period" EXHIBIT 10.16

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