Key Issues. 3.1 Following the introduction of a ‘National Model for School Improvement’, a series of proposed changes to the original agreement between the five LAs in the SEWC have been outlined in the updated agreement including changes to: Governance arrangements that ensure the LAs and the EAS are complying with requirements of the National Model for Regional Working. The way grants can be dealt with by the EAS is changed – the first change being that all grants will now be channelled through the Directors group in the first instance. There is a detailed process that explains how this will work in practice. The EAS will report on this regularly to both the directors/heads of education and the Executive Members for Education in each of the LAs. The EAS ability to provide services to other customers other than the SEWC LAs for a fee and subject to scrutiny and approval from the Joint Executive Group. The EAS may proceed with such a commission without prior JEG consent when: o the contract is valued at up to £50k but carries no risk/will have no impact on agreed delivery outcomes o the contract is valued up to £15k and may/will have an impact on agreed delivery outcomes o The EAS has taken appropriate advice on any VAT liabilities that entering into such a contract may give rise to and these are factored into the detail of the contract. o The EAS has taken appropriate legal advice in drawing up the contract. o The EAS will inform the next JEG meeting of all new contracts that exceed £10,000 over a financial year. In the event the EAS core service costs more than predicted, in line with prior JEG approval, each LA will pay its proportional share on this overspend. However, the EAS in negotiation with the LAs will repay this “loan” over an agreed period through reducing the core service charge each LA pays for an agreed period.
Key Issues. 3.1 The value of the contract that PHA has with Fermanagh and Omagh District Council for the current 2017/18 financial year is £109,287.19.
Key Issues. 2.1 Delegation of decisions in the manner requested facilitates the smooth running of the Joint Waste Board. Without such delegations in place, given that this is a high value, long term joint project involving three local authorities with central government revenue support funding, there would be a serious risk that proper and prompt decision making would prove to be very difficult, with a consequent adverse effect on the efficient operation of the PFI project
Key Issues. With help of a holistic approach increase safety and security for children going to and from school by bus.
Key Issues. Salary/Compensation Practice or System Fixed, Contingent or Both Key Issues Salary/Compensation Productivity Charges vs. Collections Practice (Projected vs. Historical) Resource, Staff Issues Profit Key Issues Salary/Compensation Signing Bonus Relocation Expenses Income Guarantee Key Issues
Key Issues. 4.3.1 The key issue is whether the development would be acceptable in principle, particularly whether it would comply with Policy 29 - Rural Housing Needs, effect on neighbouring residential amenity, the visual amenities of the locality, and highway/ parking matters.
Key Issues. 4.4.1 In the event, during Development in relation to any of the Products, the Licensor becomes aware of any reason to believe [**] the Licensor shall report such event (a, “Key Issue”) promptly to the Steering Committee [**]
Key Issues. Pursuant to Art. VII below, the following will be deemed Key Issues:
Key Issues. The key issues currently faced by Unitywater with the existing data platform are as below Business Challenges: • No unified data platform for integrated data • No formal data taxonomy in some areas • No formalised data quality • Little/No formalised data governance • Hard to get data from disparate source system to create insights • Missing opportunity due to poor data insights • Revenue loss due to undetected issues Technical Challenges: • Not designed to handle data of different variety, velocity, and volume • No support or provision of data to operational processes • No place for Data Scientist or Analyst community to explore and perform ML/AI or advanced analytics • Limited governance functions
Key Issues. The lack of a profound insight in the mechanisms of peptide-induced CD8+ T-cell response by minimal CTL peptides, explains in part their failure to induce clinical responses in human vaccination trials. • The induction of a strong T-cell response by (peptide) vaccines requires that both Ag presentation and the APC activating signals have to be matched both in time and in location. • An inherent risk of (peptide) vaccines is that not only beneficial helper CD4+ T cells but also detrimental (pre-existing) regulatory T-cells are stimulated by vaccines. • The immunotherapy of cancer will be a multi-modality approach in which synthetic (peptide) vaccines will be combined with strategies to decrease immune suppression, enhance T-cell expansion, effector potential, and T-cell homing.
